Definition of ototoxic in English:

ototoxic

adjective ˌəʊtə(ʊ)ˈtɒksɪkˌōdəˈtäksik

Medicine

Having a toxic effect on the ear or its nerve supply.
〔医〕耳毒性的
Example sentencesExamples
- It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea.
- These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents.
- Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs.
- Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible.
- Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.

Derivatives

ototoxicity

noun

Medicine

The risk of ototoxicity is not as much of an issue with the intact tympanic membrane.
Example sentencesExamples
- The potential medicolegal implications of ototoxicity, therefore, have created a dilemma: we need to determine which topical antibiotic is safe and effective in treating patients with chronic discharge from their ears.
- However, it is thought that patients with little to no drainage at the time of surgery who may be at highest risk for ototoxicity because of the lack of inflammation of the middle car mucosa to decrease the round window permeability.
- The safety profile of the formulation is generally favorable, with no demonstrable ototoxicity, nephrotoxicity, bone marrow suppression, or cardiovascular adverse effects.
- Her chest x-ray and systemic symptoms were improving, but she was experiencing some ototoxicity.

Definition of ototoxic in US English:

ototoxic

adjectiveˌōdəˈtäksik

Medicine

Having a toxic effect on the ear or its nerve supply.
〔医〕耳毒性的
Example sentencesExamples
- These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents.
- Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs.
- It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea.
- Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible.
- Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.

词汇	ototoxic
释义	Definition of ototoxic in English: ototoxic adjective ˌəʊtə(ʊ)ˈtɒksɪkˌōdəˈtäksik Medicine Having a toxic effect on the ear or its nerve supply. 〔医〕耳毒性的 Example sentencesExamples It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea. These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents. Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs. Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible. Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway. Derivatives ototoxicity noun Medicine The risk of ototoxicity is not as much of an issue with the intact tympanic membrane. Example sentencesExamples The potential medicolegal implications of ototoxicity, therefore, have created a dilemma: we need to determine which topical antibiotic is safe and effective in treating patients with chronic discharge from their ears. However, it is thought that patients with little to no drainage at the time of surgery who may be at highest risk for ototoxicity because of the lack of inflammation of the middle car mucosa to decrease the round window permeability. The safety profile of the formulation is generally favorable, with no demonstrable ototoxicity, nephrotoxicity, bone marrow suppression, or cardiovascular adverse effects. Her chest x-ray and systemic symptoms were improving, but she was experiencing some ototoxicity. Definition of ototoxic in US English: ototoxic adjectiveˌōdəˈtäksik Medicine Having a toxic effect on the ear or its nerve supply. 〔医〕耳毒性的 Example sentencesExamples These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents. Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs. It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea. Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible. Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.
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