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词汇 megaloblast
释义

Definition of megaloblast in English:

megaloblast

noun ˈmɛɡələ(ʊ)blastˈmɛɡələˌblæst
Medicine
  • A large, abnormally developed red blood cell typical of certain forms of anaemia, associated with a deficiency of folic acid or of vitamin B₁₂.

    〔医〕巨成红细胞,巨幼红细胞

    Example sentencesExamples
    • Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.
    • Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
    • Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.
    • Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.
    • Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.

Derivatives

  • megaloblastic

  • adjective
    Medicine
    • She had megaloblastic changes in the bone marrow and chronic severe liver disease.
      Example sentencesExamples
      • Iron-deficiency anaemia and megaloblastic anaemia can occur during pregnancy.
      • Three of these children revealed megaloblastic changes in bone marrow aspiration though their serum vitamin B12 and folate levels were normal.
      • Folate and vitamin D deficiency may necessitate vitamin supplementations and, if uncorrected, leads to megaloblastic anemia.
      • The classic affected patient who presents with neuropathy and megaloblastic anemia likely represents the minority of subjects with cobalamin deficiency.

Definition of megaloblast in US English:

megaloblast

nounˈmeɡələˌblastˈmɛɡələˌblæst
Medicine
  • A large, abnormally developed red blood cell typical of certain forms of anemia, associated with a deficiency of folic acid or of vitamin B₁₂.

    〔医〕巨成红细胞,巨幼红细胞

    Example sentencesExamples
    • Finding megaloblasts in the blood can help to diagnose anaemia but does not determine the cause.
    • Ehrlich distinguished 3 types of granulated white blood cells, as well as normoblasts, megaloblasts, and leukemic cells.
    • Enlarged red cells derived from megaloblasts are a consequence of a deficiency of vitamin B12 or folic acid.
    • Enlarged red cells, called megaloblasts, are caused by vitamin B12 deficiency and folate deficiency.
    • Megaloblastic anemia is characterized by the presence of megaloblasts in the bone marrow.
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