| 释义 |
Definition of quinolone in English: quinolonenoun ˈkwɪnələʊnˈkwinəˌlōn mass nounAn antibiotic derived from quinoline and used chiefly against Gram-negative organisms. 喹诺酮 （从喹啉中提取的一种抗生素，主要用来灭杀革兰氏阴性微生物） Example sentencesExamples - When used in combination with agents from other antibiotic classes, such as beta-lactams and aminoglycosides, the quinolones are not predictably synergistic.
- Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.
- The patient was treated with quinolones with significant improvement but died 1 month later, apparently from upper airway obstruction.
- Tetracycline or quinolones for a period of 6 months or until nasal biopsies are negative are recommended.
- In addition, one study reported an eightfold increase in a medication-resistant food-poisoning bacteria after the antibiotic - quinolone - was approved to be used in chickens.
- Patients with prior exposure to any of the quinolones are likely to develop resistance to other quinolones.
- The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).
- Resistance to quinolones can also develop because of alterations in bacterial permeability and the development of efflux pumps.
- These agents can bind to several drug classes including quinolones, and tetracyclines.
- The quinolones are broad-spectrum antibiotics.
- Persons who have a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents or any other components of the medication should not use levofloxacin.
- The second-generation quinolones have increased gram-negative activity, as well as some gram-positive and atypical pathogen coverage.
- New information includes the wider spread of quinolone resistance to Neisseria gonorrhoeae and the need for follow-up testing in women treated for chlamydial infection.
- Ciprofloxacin given orally shows rapid selectivity, which promotes resistance, and quinolones are not recommended in adolescents because of the associated risk of arthropathy.
- And it interacts with several common medications, including bronchodilators, the quinolone class of antibiotics, and anti-anxiety drugs.
- Because of their extensive gram-negative coverage, quinolone antibiotics were initially used to treat urinary tract infections.
- Diabetic foot infections, which are polymicrobial, can be treated with quinolones in combination with other antibiotics.
- The main chemical feature that distinguishes fluoroquinolones from the early quinolones is the presence of a fluorine at position six.
- Tendon injuries are a known important complication of treatment with quinolone antibiotics, especially in elderly people and when used in conjunction with corticosteroids.
- Future trials should also examine long term outcomes, recurrence rate, long term survival, and the development of resistant pathogens, particularly with quinolones.
Origin1930s: from quin- (in quinoline) + -one. Definition of quinolone in US English: quinolonenounˈkwinəˌlōn Any of a class of antibiotics used in treating a variety of mainly Gram-negative infections, and thought to be responsible for antibiotic resistance in some microbes. Example sentencesExamples - The quinolones are broad-spectrum antibiotics.
- The patient was treated with quinolones with significant improvement but died 1 month later, apparently from upper airway obstruction.
- The main chemical feature that distinguishes fluoroquinolones from the early quinolones is the presence of a fluorine at position six.
- New information includes the wider spread of quinolone resistance to Neisseria gonorrhoeae and the need for follow-up testing in women treated for chlamydial infection.
- These agents can bind to several drug classes including quinolones, and tetracyclines.
- When used in combination with agents from other antibiotic classes, such as beta-lactams and aminoglycosides, the quinolones are not predictably synergistic.
- Ciprofloxacin given orally shows rapid selectivity, which promotes resistance, and quinolones are not recommended in adolescents because of the associated risk of arthropathy.
- Diabetic foot infections, which are polymicrobial, can be treated with quinolones in combination with other antibiotics.
- Resistance to quinolones can also develop because of alterations in bacterial permeability and the development of efflux pumps.
- And it interacts with several common medications, including bronchodilators, the quinolone class of antibiotics, and anti-anxiety drugs.
- Future trials should also examine long term outcomes, recurrence rate, long term survival, and the development of resistant pathogens, particularly with quinolones.
- Persons who have a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents or any other components of the medication should not use levofloxacin.
- Drugs that have been implicated include penicillin, aminopenicillins, sulfonamides, allopurinol, thiazides, quinolones, hydantoins, and propylthiouracil.
- In addition, one study reported an eightfold increase in a medication-resistant food-poisoning bacteria after the antibiotic - quinolone - was approved to be used in chickens.
- Because of their extensive gram-negative coverage, quinolone antibiotics were initially used to treat urinary tract infections.
- Tetracycline or quinolones for a period of 6 months or until nasal biopsies are negative are recommended.
- The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).
- Patients with prior exposure to any of the quinolones are likely to develop resistance to other quinolones.
- Tendon injuries are a known important complication of treatment with quinolone antibiotics, especially in elderly people and when used in conjunction with corticosteroids.
- The second-generation quinolones have increased gram-negative activity, as well as some gram-positive and atypical pathogen coverage.
Origin1930s: from quin- (in quinoline) + -one. |