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词汇 mesenchyme
释义

Definition of mesenchyme in English:

mesenchyme

noun ˈmɛsəŋkʌɪmˈmiːzəŋkʌɪm
mass nounEmbryology
  • A loosely organized, mainly mesodermal embryonic tissue which develops into connective and skeletal tissues, including blood and lymph.

    〔胚〕间充(质)

    Example sentencesExamples
    • The branchial arches begin as cylindrical cores of mesenchyme sandwiched between continuous sheets of epidermal ectoderm and internal endoderm.
    • Mutations that disrupt the signaling interactions between epithelium and the underlying mesenchyme can cause eyelid closure defects.
    • Other matrix proteins, such as fibronection, are also present throughout developing lung mesenchyme and at tips of secondary septae in the alveolar stage.
    • What's more, these commands are part of the developmental vocabulary of mesenchyme cells generally, and are understood in more or less the same way throughout the embryo.
    • The critical process depends upon whether the ectoderm can contact a condensate of specialized mesenchyme called the dermal papillae.
    • There is some mesenchyme in the core toward the base, however, they are very different in structure.
    • The lenticular process is actually derived from mesenchyme attributed to the second branchial (hyoid).
    • The mesoderm also provides the mesenchyme (by sinking of cells from its epithelium into the extracellular matrix) from which organ development becomes possible.
    • The intervertebral discs develop embryologically from both the mesenchyme (the annulus fibrosus) and the notochord (the nucleus pulposus).
    • The subcoelomic mesenchyme is defined as the layer of tissue that lies underneath the mesothelial surface of the peritoneum.
    • Classical embryology long ago demonstrated that grafting dental epithelium onto non-dental mesenchyme could produce tooth-like structures if the experiment were performed early enough in development.
    • To understand the origins of complexity in metazoan body plans, then, we must find where these tissues came from; that is, how epithelia and mesenchyme arose.
    • In the sea-urchin embryo, for instance, the primary mesenchyme originates from epithelial cells of the blastula by their losing cadherins and producing enzymes that allow them to invade the basal lamina.
    • One type tends to form surface tissues or epithelium, the other becomes mesenchyme, the tissue that holds us together and becomes blood vessels.
    • Fertilization occurs in the mesenchyme and the zygotes develop into ciliated larvae.
    • The mammary glands also develop under sequential reciprocal interactions between the epithelium and adjacent mesenchyme.
    • These are lined by a thick layer of nasal epithelium surrounded by the mesenchyme of the placode.
    • Derived from embryonic mesoderm, mesenchyme is the first connective tissue formed.
    • These include the epidermis and inner tunic and some mesenchyme derivatives which have differentiated into blood cells in the larva.
    • That of course takes the problem back in time as to where or what organized the collagenous lattice in the dermal mesenchyme, but let's not get into that.

Derivatives

  • mesenchymal

  • adjective
    Embryology
    • All animals, including the essentially epithelial cnidarians, nevertheless have the capacity to produce mesenchymal cells.
      Example sentencesExamples
      • The transcription factors that promote epithelial cells are repressed in order to produce mesenchymal cells.
      • There is no doubt that a lattice does exist, and mesenchymal cells certainly line up along it.
      • In vertebrates, the limb apical epidermis promotes proliferation and inhibits differentiation of underlying mesenchymal cells.
      • While turning an undistinguished group of mesenchymal cells into muscle is a complex transformation, that transformation can be turned on or off with a set of very simple commands.
  • mesenchymatous

  • adjective
    Embryology

Origin

Late 19th century: from Greek mesos 'middle' + enkhuma 'infusion'.

Definition of mesenchyme in US English:

mesenchyme

noun
Embryology
  • A loosely organized, mainly mesodermal embryonic tissue which develops into connective and skeletal tissues, including blood and lymph.

    〔胚〕间充(质)

    Example sentencesExamples
    • Mutations that disrupt the signaling interactions between epithelium and the underlying mesenchyme can cause eyelid closure defects.
    • The intervertebral discs develop embryologically from both the mesenchyme (the annulus fibrosus) and the notochord (the nucleus pulposus).
    • The subcoelomic mesenchyme is defined as the layer of tissue that lies underneath the mesothelial surface of the peritoneum.
    • The branchial arches begin as cylindrical cores of mesenchyme sandwiched between continuous sheets of epidermal ectoderm and internal endoderm.
    • The mesoderm also provides the mesenchyme (by sinking of cells from its epithelium into the extracellular matrix) from which organ development becomes possible.
    • Derived from embryonic mesoderm, mesenchyme is the first connective tissue formed.
    • One type tends to form surface tissues or epithelium, the other becomes mesenchyme, the tissue that holds us together and becomes blood vessels.
    • In the sea-urchin embryo, for instance, the primary mesenchyme originates from epithelial cells of the blastula by their losing cadherins and producing enzymes that allow them to invade the basal lamina.
    • That of course takes the problem back in time as to where or what organized the collagenous lattice in the dermal mesenchyme, but let's not get into that.
    • These include the epidermis and inner tunic and some mesenchyme derivatives which have differentiated into blood cells in the larva.
    • There is some mesenchyme in the core toward the base, however, they are very different in structure.
    • Fertilization occurs in the mesenchyme and the zygotes develop into ciliated larvae.
    • To understand the origins of complexity in metazoan body plans, then, we must find where these tissues came from; that is, how epithelia and mesenchyme arose.
    • What's more, these commands are part of the developmental vocabulary of mesenchyme cells generally, and are understood in more or less the same way throughout the embryo.
    • The critical process depends upon whether the ectoderm can contact a condensate of specialized mesenchyme called the dermal papillae.
    • Classical embryology long ago demonstrated that grafting dental epithelium onto non-dental mesenchyme could produce tooth-like structures if the experiment were performed early enough in development.
    • Other matrix proteins, such as fibronection, are also present throughout developing lung mesenchyme and at tips of secondary septae in the alveolar stage.
    • The mammary glands also develop under sequential reciprocal interactions between the epithelium and adjacent mesenchyme.
    • These are lined by a thick layer of nasal epithelium surrounded by the mesenchyme of the placode.
    • The lenticular process is actually derived from mesenchyme attributed to the second branchial (hyoid).

Origin

Late 19th century: from Greek mesos ‘middle’ + enkhuma ‘infusion’.

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