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词汇 depolymerize
释义

Definition of depolymerize in English:

depolymerize

(British depolymerise)
verbdiːˈpɒlɪmərʌɪzdēˈpäləməˌrīz
[with object]Chemistry
  • 1Break (a polymer) down into monomers or other smaller units.

    〔化〕使(聚合物)解聚

    Example sentencesExamples
    • These pharmacological agents depolymerize microtubules and actin respectively.
    • When nocodazole was used to depolymerize microtubules in the cell periphery, we observed a significant increase of failures to initiate compared to untreated cells.
    • Eleven mutants whose decline in viability was fully or partly suppressed by depolymerizing the spindle were retained.
    • Second, the separate filaments depolymerize into monomers.
    • The largest shift in molecular weight occurred during the melting stage, but matrix glycans remained at moderately high molecular weight even in overripe fruit, and were not depolymerized to small size.
    1. 1.1no object Undergo the process of depolymerization.
      the ideal disposable polymer would depolymerize naturally

      理想的一次性聚合物会自然解聚。

      Example sentencesExamples
      • A simple model would be one in which actin on one side of a patch is polymerizing while the other side is depolymerizing.
      • Others have suggested that cofilin depolymerizes by severing filaments and capping their barbed ends.
      • Some of these short caps broke off when the actin monomers were washed out; the rest depolymerized within 300 s.
      • This suggests that the distribution of minus ends where microtubules depolymerize and thus, the pole itself, extends over a large area.
      • Says Nogales, ‘That the rings remain attached to the microtubule end as it depolymerizes, is a most ingenious mechanism to move chromosome to the two daughter cells during anaphase, without even requiring energy.’

Derivatives

  • depolymerization

  • noundiːpɒlɪmərʌɪˈzeɪʃ(ə)n
    Chemistry
    • We used a low dose of the drug to prevent catastrophic depolymerization of actin and major morphological changes, which both would have biased our analysis.
      Example sentencesExamples
      • For example, tropomyosin, a coiled-coil protein that binds along the sides of actin filaments, inhibits the rate of depolymerization from the pointed end, without affecting elongation.
      • The dynamics of actin polymerization and depolymerization in the absence of crosslinkers has been mathematically modeled by others, and was theoretically shown to yield a steady-state exponential length distribution.
      • The development of leatheriness showed a similar lack of polyuronide depolymerization, with no detectable depolymerization relative to pre-ripening and a greater arrest of depolymerization than in mealy fruit.
      • Does actin polymerization restart from nucleation sites that are retained at the membrane during the depolymerization of actin, or can repolymerization begin anywhere in the cell and be subsequently coupled to membrane protrusion?

Definition of depolymerize in US English:

depolymerize

(British depolymerise)
verbdēˈpäləməˌrīz
[with object]Chemistry
  • 1Break (a polymer) down into monomers or other smaller units.

    〔化〕使(聚合物)解聚

    Example sentencesExamples
    • When nocodazole was used to depolymerize microtubules in the cell periphery, we observed a significant increase of failures to initiate compared to untreated cells.
    • Eleven mutants whose decline in viability was fully or partly suppressed by depolymerizing the spindle were retained.
    • Second, the separate filaments depolymerize into monomers.
    • These pharmacological agents depolymerize microtubules and actin respectively.
    • The largest shift in molecular weight occurred during the melting stage, but matrix glycans remained at moderately high molecular weight even in overripe fruit, and were not depolymerized to small size.
    1. 1.1no object Undergo the process of depolymerization.
      the ideal disposable polymer would depolymerize naturally

      理想的一次性聚合物会自然解聚。

      Example sentencesExamples
      • This suggests that the distribution of minus ends where microtubules depolymerize and thus, the pole itself, extends over a large area.
      • Others have suggested that cofilin depolymerizes by severing filaments and capping their barbed ends.
      • A simple model would be one in which actin on one side of a patch is polymerizing while the other side is depolymerizing.
      • Says Nogales, ‘That the rings remain attached to the microtubule end as it depolymerizes, is a most ingenious mechanism to move chromosome to the two daughter cells during anaphase, without even requiring energy.’
      • Some of these short caps broke off when the actin monomers were washed out; the rest depolymerized within 300 s.
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