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词汇 methylate
释义

Definition of methylate in English:

methylate

verb ˈmɛθɪleɪtˈmɛθəˌleɪt
[with object]often as adjective methylated
  • 1Mix or impregnate with methanol or methylated spirit.

    在…中加甲醇(或甲基化酒精)

    a portable stove which burned methylated briquettes
    1. 1.1Chemistry Introduce a methyl group into (a molecule or compound)
      〔化〕使(分子或化合物)甲基化
      the cytosine moiety in the chromosomal DNA is usually methylated
      Example sentencesExamples
      • In many organisms, nuclear DNA is methylated at cytosine residues, resulting in 5-methylcytosine.
      • An enzyme that methylates the carboxyl side chain of IAA has recently been described.
      • Some molecules are heavily methylated while others are not, consistent with our previous observations.
      • When this hydroxyl group is then methylated to give there is a very significant, 3000-fold, decrease in inhibitor binding.
      • The ability of these compounds to methylate DNA, however, correlated with the biological activity.

Derivatives

  • methylation

  • noun mɛθɪˈleɪʃ(ə)n
    • Because methylation is secondary to replication, newly synthesized DNA transiently exists as hemimethylated molecule.
      Example sentencesExamples
      • Thus it not only had nucleosomes and histone acetylation and methylation, but was also sexual with meiosis and a bouquet stage.
      • After methylation, DNA was extracted with phenol-chloroform followed by ethanol precipitation.
      • Some of the resulting methylations may have desired effects but other methylations near other genes might cause effects that are harmful.
      • DNA methylation is a common molecular alteration in colorectal cancer cells.

Definition of methylate in US English:

methylate

verbˈmɛθəˌleɪtˈmeTHəˌlāt
[with object]often as adjective methylated
  • 1Mix or impregnate with methanol or methylated spirit.

    在…中加甲醇(或甲基化酒精)

    a portable stove which burned methylated briquettes
    1. 1.1Chemistry Introduce a methyl group into (a molecule or compound)
      〔化〕使(分子或化合物)甲基化
      the cytosine moiety in the chromosomal DNA is usually methylated
      Example sentencesExamples
      • The ability of these compounds to methylate DNA, however, correlated with the biological activity.
      • When this hydroxyl group is then methylated to give there is a very significant, 3000-fold, decrease in inhibitor binding.
      • In many organisms, nuclear DNA is methylated at cytosine residues, resulting in 5-methylcytosine.
      • An enzyme that methylates the carboxyl side chain of IAA has recently been described.
      • Some molecules are heavily methylated while others are not, consistent with our previous observations.
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