Definition of hypermutable in English:

hypermutable

adjective hʌɪpəˈmjʊːtəb(ə)lˌhīpərˈmyo͞odəb(ə)l

Genetics

Of or in a state in which mutation is abnormally frequent.
〔遗传〕超突变的
Example sentencesExamples
- As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles.
- High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites.
- After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site.
- The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides.
- The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides.

Derivatives

hypermutation

noun ˌhʌɪpəmjuːˈteɪʃ(ə)nˈˌhaɪpərˌmjuˈteɪʃ(ə)n

mass noun

Genetics

Mutation that is abnormally frequent.
〔遗传〕超突变的
we observed hypermutation in one of the viral strains
Example sentencesExamples
- For example, somatic hypermutation of Ig genes is used to generate antibodies with increased antigen affinity.
- Among the progeny, a variable proportion suffer hypermutation (C-to-T transitions) of both copies of the gene.
- The corresponding near-neighbors had to be removed because not all putative CG tandems are generated by CG hypermutation.

Definition of hypermutable in US English:

hypermutable

adjectiveˌhīpərˈmyo͞odəb(ə)l

Genetics

Of or in a state in which mutation is abnormally frequent.
〔遗传〕超突变的
Example sentencesExamples
- The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides.
- After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site.
- As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles.
- High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites.
- The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides.

词汇	hypermutable
释义	Definition of hypermutable in English: hypermutable adjective hʌɪpəˈmjʊːtəb(ə)lˌhīpərˈmyo͞odəb(ə)l Genetics Of or in a state in which mutation is abnormally frequent. 〔遗传〕超突变的 Example sentencesExamples As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles. High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites. After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site. The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides. The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides. Derivatives hypermutation noun ˌhʌɪpəmjuːˈteɪʃ(ə)nˈˌhaɪpərˌmjuˈteɪʃ(ə)n mass nounGenetics Mutation that is abnormally frequent. 〔遗传〕超突变的 we observed hypermutation in one of the viral strains Example sentencesExamples For example, somatic hypermutation of Ig genes is used to generate antibodies with increased antigen affinity. Among the progeny, a variable proportion suffer hypermutation (C-to-T transitions) of both copies of the gene. The corresponding near-neighbors had to be removed because not all putative CG tandems are generated by CG hypermutation. Definition of hypermutable in US English: hypermutable adjectiveˌhīpərˈmyo͞odəb(ə)l Genetics Of or in a state in which mutation is abnormally frequent. 〔遗传〕超突变的 Example sentencesExamples The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides. After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site. As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles. High GC may cause elevated substitution rates, e.g., by a higher incidence of hypermutable CpG sites. The high rate of evolution in ancestral repeats may be due partly to higher levels of hypermutable CpG dinucleotides.
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