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词汇 Paget's disease
释义

Definition of Paget's disease in English:

Paget's disease

nounˈpadʒɪtsˈpædʒəts dəˌziz
mass noun
  • 1A chronic disease of elderly people characterized by alteration of bone tissue, especially in the spine, skull, or pelvis, sometimes causing severe pain.

    佩吉特氏病,变形性骨炎

    Also called osteitis deformans
    Example sentencesExamples
    • It is indicated for the treatment of osteoporosis in post-menopausal women and the treatment of Paget's disease of bone.
    • Conditions such as an uncorrected fracture of the shin bone, rheumatoid arthritis, osteoarthritis or Paget's disease can distort the ends of the bones and cause knock knee in adults.
    • Because of their relative safety, bisphosphonates have been labeled (for more than two decades) for the treatment of metabolic bone disorders such as Paget's disease.
    • The radiologist reported changes consistent with Paget's disease of the bone.
    • Patients with bone pain caused by Paget's disease usually describe the pain as continuous.
  • 2An inflammation of the nipple associated with breast cancer.

    佩吉特氏病,乳晕乳头炎性癌变

    Example sentencesExamples
    • The rash might have been eczema or dermatitis, but its location made me worry about Paget's disease of the breast.
    • A rash, redness, scaliness around the nipple or itching that lasts several weeks could also be a sign of eczema or Paget's disease, a rare form of breast cancer.
    • In about half of the cases of Paget's disease there is a lump which indicates that the underlying cancer is more developed.
    • You are correct to worry that a rash on the nipple areola area could be Paget's disease, but if the nipple itself is not involved this is much less likely.
    • A prolonged rash or irritation of the nipple may indicate a special kind of breast cancer called Paget's disease, which specifically affects the nipple.

Origin

Late 19th century: named after Sir James Paget (1814–99), English surgeon.

Definition of Paget's disease in US English:

Paget's disease

nounˈpædʒəts dəˌzizˈpajəts dəˌzēz
  • 1A chronic disease of elderly people characterized by deterioration of bone tissue, especially in the spine, skull, or pelvis, sometimes causing severe pain.

    佩吉特氏病,变形性骨炎

    Also called osteitis deformans
    Example sentencesExamples
    • Patients with bone pain caused by Paget's disease usually describe the pain as continuous.
    • The radiologist reported changes consistent with Paget's disease of the bone.
    • It is indicated for the treatment of osteoporosis in post-menopausal women and the treatment of Paget's disease of bone.
    • Because of their relative safety, bisphosphonates have been labeled (for more than two decades) for the treatment of metabolic bone disorders such as Paget's disease.
    • Conditions such as an uncorrected fracture of the shin bone, rheumatoid arthritis, osteoarthritis or Paget's disease can distort the ends of the bones and cause knock knee in adults.
  • 2An inflammation of the nipple associated with breast cancer.

    佩吉特氏病,乳晕乳头炎性癌变

    Example sentencesExamples
    • A prolonged rash or irritation of the nipple may indicate a special kind of breast cancer called Paget's disease, which specifically affects the nipple.
    • You are correct to worry that a rash on the nipple areola area could be Paget's disease, but if the nipple itself is not involved this is much less likely.
    • In about half of the cases of Paget's disease there is a lump which indicates that the underlying cancer is more developed.
    • A rash, redness, scaliness around the nipple or itching that lasts several weeks could also be a sign of eczema or Paget's disease, a rare form of breast cancer.
    • The rash might have been eczema or dermatitis, but its location made me worry about Paget's disease of the breast.

Origin

Late 19th century: named after Sir James Paget (1814–99), English surgeon.

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