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词汇 inosine
释义

Definition of inosine in English:

inosine

noun ˈɪnə(ʊ)siːn
mass nounBiochemistry
  • A compound which is an intermediate in the metabolism of purine and is used in kidney transplantation to provide a temporary source of sugar. It is a nucleoside consisting of hypoxanthine linked to ribose.

    〔生化〕次黄嘌呤核苷,肌苷

    Example sentencesExamples
    • Apart from that, however, they would exhibit exactly the same coordination of the ions as in the channel of the guanine quadruplex as the electronic structure and molecular electrostatic potential of inosine and guanine are similar.
    • Adenosine deaminase is an aminohydrolase that converts adenosine to inosine and is thus involved in the catabolism of purine bases.
    • However, due to the low transport rate of inosine, this is a low-flux pathway.
    • Adenosine deaminase is an enzyme of purine metabolism which catalyses adenosine into inosine and is found in most human tissues particularly in the lymphoid tissues.
    • We have evaluated selected molecular interactions of nucleobases in the simulated structures to obtain further insight in similarities and differences between the ability of guanine and inosine to form quadruplexes.

Origin

Early 20th century: from Greek is, in- 'fibre, muscle' + -ose2 + -ine4.

Definition of inosine in US English:

inosine

noun
Biochemistry
  • A compound which is an intermediate in the metabolism of purine and is used in kidney transplantation to provide a temporary source of sugar. It is a nucleoside consisting of hypoxanthine linked to ribose.

    〔生化〕次黄嘌呤核苷,肌苷

    Example sentencesExamples
    • Apart from that, however, they would exhibit exactly the same coordination of the ions as in the channel of the guanine quadruplex as the electronic structure and molecular electrostatic potential of inosine and guanine are similar.
    • However, due to the low transport rate of inosine, this is a low-flux pathway.
    • We have evaluated selected molecular interactions of nucleobases in the simulated structures to obtain further insight in similarities and differences between the ability of guanine and inosine to form quadruplexes.
    • Adenosine deaminase is an aminohydrolase that converts adenosine to inosine and is thus involved in the catabolism of purine bases.
    • Adenosine deaminase is an enzyme of purine metabolism which catalyses adenosine into inosine and is found in most human tissues particularly in the lymphoid tissues.

Origin

Early 20th century: from Greek is, in- ‘fiber, muscle’ + -ose + -ine.

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