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词汇 spermine
释义

Definition of spermine in English:

spermine

noun ˈspəːmiːnˈspərmēn
mass nounBiochemistry
  • A deliquescent compound which acts to stabilize various components of living cells and is widely distributed in living and decaying tissues.

    〔生化〕精胺,第二性征激素

    A polyamine; chemical formula: (H₂N(CH₂)₃NH(CH₂)₂)₂. Compare with spermidine

    Example sentencesExamples
    • The binding model displayed in Fig.8 A has been observed from crystallographic studies on B-DNA dodecamers stabilized with spermine.
    • The flexible polyamine spermine displays a high presence in the minor groove but does not form long-lived and structurally defined complexes.
    • This may be related to the role of arginine as a biochemical precursor in the synthesis of putrescine, spermidine, and spermine, which are believed to be essential to sperm motility.
    • By comparison, the tetra-amine spermine only binds weakly to peptide carboxylate groups, and not to the a-helical conformation.
    • Because of their positive charges, putrescine, spermidine, and spermine show a high affinity with the acidic constituents of the cell (RNA, DNA, ATP, acidic proteins, phospholipids, etc.).

Origin

Late 19th century: so called because first found in sperm.

Definition of spermine in US English:

spermine

nounˈspərmēn
Biochemistry
  • A deliquescent compound which acts to stabilize various components of living cells and is widely distributed in living and decaying tissues.

    〔生化〕精胺,第二性征激素

    A polyamine; chemical formula: (H₂N(CH₂)₃NH(CH₂)₂)₂

    Example sentencesExamples
    • The flexible polyamine spermine displays a high presence in the minor groove but does not form long-lived and structurally defined complexes.
    • This may be related to the role of arginine as a biochemical precursor in the synthesis of putrescine, spermidine, and spermine, which are believed to be essential to sperm motility.
    • The binding model displayed in Fig.8 A has been observed from crystallographic studies on B-DNA dodecamers stabilized with spermine.
    • By comparison, the tetra-amine spermine only binds weakly to peptide carboxylate groups, and not to the a-helical conformation.
    • Because of their positive charges, putrescine, spermidine, and spermine show a high affinity with the acidic constituents of the cell (RNA, DNA, ATP, acidic proteins, phospholipids, etc.).

Origin

Late 19th century: so called because first found in sperm.

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