Definition of episome in English:

episome

noun ˈɛpɪsəʊmˈepəˌsōm

Microbiology

A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated.
〔微生物〕附加体，游离体；游离基因。比较PLASMID
Compare with plasmid
Example sentencesExamples
- This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128.
- Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells.
- The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome.
- Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability.
- During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted.

Origin

1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some.

Definition of episome in US English:

episome

nounˈepəˌsōm

Microbiology

A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated.
〔微生物〕附加体，游离体；游离基因。比较PLASMID
Compare with plasmid
Example sentencesExamples
- The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome.
- During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted.
- Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability.
- This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128.
- Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells.

Origin

1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some.

词汇	episome
释义	Definition of episome in English: episome noun ˈɛpɪsəʊmˈepəˌsōm Microbiology A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated. 〔微生物〕附加体，游离体；游离基因。比较PLASMID Compare with plasmid Example sentencesExamples This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128. Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells. The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome. Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability. During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted. Origin 1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some. Definition of episome in US English: episome nounˈepəˌsōm Microbiology A genetic element inside some bacterial cells, especially the DNA of some bacteriophages, that can replicate independently of the host and also in association with a chromosome with which it becomes integrated. 〔微生物〕附加体，游离体；游离基因。比较PLASMID Compare with plasmid Example sentencesExamples The uppermost cell in a colony has a conical episome; the bottom cell in a colony has a bilobed hyposome. During latent infection, the viral genome persists as an episome, and viral gene expression is highly restricted. Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability. This attribute does not appear to be a feature of other independently isolated episomes, including episomes that cover the same portion of the E. coli chromosome that is included in F'128. Lieberman and his colleagues found that the three telomeric proteins might help Epstein-Barr virus episomes persist in cells. Origin 1930s (denoting a particle postulated as a constituent of a gene): from epi- + -some.
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