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词汇 epistasis
释义

Definition of epistasis in English:

epistasis

noun ɪˈpɪstəsɪsəˈpistəsəs
mass nounGenetics
  • The interaction of genes that are not alleles, in particular the suppression of the effect of one such gene by another.

    〔遗传〕上位性,异位显性

    Example sentencesExamples
    • For geneticists, epistasis is associated with the limits of the additive model of gene action.
    • This advantage of sex should be especially substantial when mutations interact through negative epistasis.
    • These results suggest that future genetic models for the evolution of aging should incorporate the effects of epistasis.
    • Genetic epistasis of gene expression can also be considered with large sample sizes.
    • Neither earlier study was able to demonstrate a significant effect of epistasis, either positive or negative.

Derivatives

  • epistatic

  • adjective ˌɛpɪˈstatɪk
    Genetics
    • Thus, neither allele is epistatic to the other in permitting the occurrence of expansions or contractions.
      Example sentencesExamples
      • It is known that epistatic selection may produce significant linkage disequilibrium in natural populations.
      • Such sites may be indicative of hotspots of recombination or mutation or epistatic selection.
      • The results suggested that a minimum of two genes with epistatic effects were involved in the genetic control of cleistogamy.
      • This study shows that most hybrid incompatibilities are recessive and epistatic.

Origin

Early 19th century: from Greek, literally 'stoppage', from ephistanai 'to stop'.

Definition of epistasis in US English:

epistasis

nounəˈpistəsəs
Genetics
  • The interaction of genes that are not alleles, in particular the suppression of the effect of one such gene by another.

    〔遗传〕上位性,异位显性

    Example sentencesExamples
    • For geneticists, epistasis is associated with the limits of the additive model of gene action.
    • Genetic epistasis of gene expression can also be considered with large sample sizes.
    • These results suggest that future genetic models for the evolution of aging should incorporate the effects of epistasis.
    • This advantage of sex should be especially substantial when mutations interact through negative epistasis.
    • Neither earlier study was able to demonstrate a significant effect of epistasis, either positive or negative.

Origin

Early 19th century: from Greek, literally ‘stoppage’, from ephistanai ‘to stop’.

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