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词汇 epitope
释义

Definition of epitope in English:

epitope

noun ˈɛpɪtəʊpˈepəˌtōp
Biochemistry
  • The part of an antigen molecule to which an antibody attaches itself.

    〔生化〕表位,抗原决定部位,抗原决定基。亦称ANTIGENIC DETERMINANT

    Also called antigenic determinant
    Example sentencesExamples
    • The loci of the known epitopes of the antibodies used are shown diagrammatically in Fig.1.
    • Even in the case of microbial antigens not found in vertebrates such as lipopolysaccharides, it should be noted that peptide epitopes can mimic bacterial carbohydrates and DNA.
    • We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies.
    • On cell-surface glycoproteins, the epitope structure of TF antigen is linked to either serines or threonines.
    • In all the experiments on native titin, the molecule was attached to two beads, each labeled with an antibody to a different epitope.

Origin

1960s: from epi- 'upon' + Greek topos 'place'.

Definition of epitope in US English:

epitope

nounˈepəˌtōp
Biochemistry
  • The part of an antigen molecule to which an antibody attaches itself.

    〔生化〕表位,抗原决定部位,抗原决定基。亦称ANTIGENIC DETERMINANT

    Also called antigenic determinant
    Example sentencesExamples
    • In all the experiments on native titin, the molecule was attached to two beads, each labeled with an antibody to a different epitope.
    • On cell-surface glycoproteins, the epitope structure of TF antigen is linked to either serines or threonines.
    • We chose to consider residue charge because of evidence that the pattern of residue charges is important in determining epitopes for antibodies.
    • Even in the case of microbial antigens not found in vertebrates such as lipopolysaccharides, it should be noted that peptide epitopes can mimic bacterial carbohydrates and DNA.
    • The loci of the known epitopes of the antibodies used are shown diagrammatically in Fig.1.

Origin

1960s: from epi- ‘upon’ + Greek topos ‘place’.

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