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词汇 Muller's ratchet
释义

Definition of Muller's ratchet in English:

Muller's ratchet

(also Muller ratchet, Muller's Ratchet)
noun ˌmʊləz ˈratʃɪt
Genetics
  • A hypothetical mechanism having the effect of invariably increasing the number of harmful mutations in a population of asexually reproducing organisms, since genotypes with the fewest harmful mutations will be among those lost at random in an irreversible manner (likened to a ratchet).

Origin

1970s; earliest use found in Genetics. From the genitive of the name of Hermann Joseph Muller, U.S. geneticist, who proposed the theory in 1964 (Mutation Res. 1 2) + ratchet. In some forms from Muller + ratchet.

Definition of Muller's ratchet in US English:

Muller's ratchet

(also Muller ratchet, Muller's Ratchet)
nounˌmʊləz ˈratʃɪt
Genetics
  • A hypothetical mechanism having the effect of invariably increasing the number of harmful mutations in a population of asexually reproducing organisms, since genotypes with the fewest harmful mutations will be among those lost at random in an irreversible manner (likened to a ratchet).

Origin

1970s; earliest use found in Genetics. From the genitive of the name of Hermann Joseph Muller, U.S. geneticist, who proposed the theory in 1964 ( Mutation Res 1 2) + ratchet. In some forms from Muller + ratchet.

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