Definition of presynaptic in English:

presynaptic

adjective ˌpriːsɪˈnaptɪkˌprēsəˈnaptik

Physiology

Relating to or denoting a nerve cell that releases a transmitter substance into a synapse during transmission of an impulse.
〔生理〕突触前的
the presynaptic terminal
Example sentencesExamples
- The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings.
- Postsynaptic proteins receive the neurotransmitters released by presynaptic proteins.
- This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell.
- The toxin irreversibly binds to presynaptic cholinergic receptors at motor nerve terminals and is subsequently internalized.
- The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons.
- The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems.
- Instead, transmission is accomplished by the release of a chemical neurotransmitter substance from the presynaptic fibre.
- With this low level of presynaptic stimulation, quantal currents could be resolved.
- In presynaptic inhibition, synapses are temporarily ‘decommissioned’ to weaken the response; but in other cases, they are added to strengthen it.
- It does so by blocking the normal presynaptic reuptake, causing an increase in function or activity level of these transmitters.
- Molecular features of the phasic and tonic presynaptic nerve terminals are currently under investigation.
- A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities.
- The authors proposed a mechanism of action whereby the calcium channel blocker inhibited the presynaptic release of neurotransmitters.
- From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered.
- Most of the clinically significant symptoms of dissociatives are produced by presynaptic dopamine stimulation and cholinergic antagonism.
- The properties of the presynaptic neuron can also be influenced by the cell with which it makes a synapse.
- Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron.
- Alpha - 2 receptors are located on the presynaptic neuron.
- Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft.
- The release of neurotransmitter is variable and dependent on the properties of the presynaptic terminal.

Derivatives

presynaptically

adverb

Physiology

We find that the occurrence of glia postsynaptically is strikingly higher than presynaptically, in both types of synapses.
Example sentencesExamples
- Cocaine blocks the reuptake of catecholamines presynaptically.
- Glutamate is released presynaptically and binds to a postsynaptic receptor gating a cation-selective channel, thus depolarizing the post-synaptic cell.

Definition of presynaptic in US English:

presynaptic

adjectiveˌprēsəˈnaptik

Physiology

Relating to or denoting a nerve cell that releases a transmitter substance into a synapse during transmission of an impulse.
〔生理〕突触前的
the presynaptic terminal
Example sentencesExamples
- The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems.
- Alpha - 2 receptors are located on the presynaptic neuron.
- The authors proposed a mechanism of action whereby the calcium channel blocker inhibited the presynaptic release of neurotransmitters.
- Instead, transmission is accomplished by the release of a chemical neurotransmitter substance from the presynaptic fibre.
- Most of the clinically significant symptoms of dissociatives are produced by presynaptic dopamine stimulation and cholinergic antagonism.
- Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft.
- The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings.
- With this low level of presynaptic stimulation, quantal currents could be resolved.
- This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell.
- Molecular features of the phasic and tonic presynaptic nerve terminals are currently under investigation.
- The toxin irreversibly binds to presynaptic cholinergic receptors at motor nerve terminals and is subsequently internalized.
- A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities.
- From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered.
- In presynaptic inhibition, synapses are temporarily ‘decommissioned’ to weaken the response; but in other cases, they are added to strengthen it.
- The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons.
- Postsynaptic proteins receive the neurotransmitters released by presynaptic proteins.
- It does so by blocking the normal presynaptic reuptake, causing an increase in function or activity level of these transmitters.
- The properties of the presynaptic neuron can also be influenced by the cell with which it makes a synapse.
- Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron.
- The release of neurotransmitter is variable and dependent on the properties of the presynaptic terminal.

词汇	presynaptic
释义	Definition of presynaptic in English: presynaptic adjective ˌpriːsɪˈnaptɪkˌprēsəˈnaptik Physiology Relating to or denoting a nerve cell that releases a transmitter substance into a synapse during transmission of an impulse. 〔生理〕突触前的 the presynaptic terminal Example sentencesExamples The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings. Postsynaptic proteins receive the neurotransmitters released by presynaptic proteins. This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell. The toxin irreversibly binds to presynaptic cholinergic receptors at motor nerve terminals and is subsequently internalized. The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons. The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems. Instead, transmission is accomplished by the release of a chemical neurotransmitter substance from the presynaptic fibre. With this low level of presynaptic stimulation, quantal currents could be resolved. In presynaptic inhibition, synapses are temporarily ‘decommissioned’ to weaken the response; but in other cases, they are added to strengthen it. It does so by blocking the normal presynaptic reuptake, causing an increase in function or activity level of these transmitters. Molecular features of the phasic and tonic presynaptic nerve terminals are currently under investigation. A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities. The authors proposed a mechanism of action whereby the calcium channel blocker inhibited the presynaptic release of neurotransmitters. From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered. Most of the clinically significant symptoms of dissociatives are produced by presynaptic dopamine stimulation and cholinergic antagonism. The properties of the presynaptic neuron can also be influenced by the cell with which it makes a synapse. Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron. Alpha - 2 receptors are located on the presynaptic neuron. Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft. The release of neurotransmitter is variable and dependent on the properties of the presynaptic terminal. Derivatives presynaptically adverb Physiology We find that the occurrence of glia postsynaptically is strikingly higher than presynaptically, in both types of synapses. Example sentencesExamples Cocaine blocks the reuptake of catecholamines presynaptically. Glutamate is released presynaptically and binds to a postsynaptic receptor gating a cation-selective channel, thus depolarizing the post-synaptic cell. Definition of presynaptic in US English: presynaptic adjectiveˌprēsəˈnaptik Physiology Relating to or denoting a nerve cell that releases a transmitter substance into a synapse during transmission of an impulse. 〔生理〕突触前的 the presynaptic terminal Example sentencesExamples The vesicles within the presynaptic axonal varicosities store the neurotransmitters that are synthesized there by special biochemical systems. Alpha - 2 receptors are located on the presynaptic neuron. The authors proposed a mechanism of action whereby the calcium channel blocker inhibited the presynaptic release of neurotransmitters. Instead, transmission is accomplished by the release of a chemical neurotransmitter substance from the presynaptic fibre. Most of the clinically significant symptoms of dissociatives are produced by presynaptic dopamine stimulation and cholinergic antagonism. Depolarization of the presynaptic membrane causes release of acetylcholine into the synaptic cleft. The second mechanism of TCA cardiotoxicity involves the blockade of norepinephrine uptake at the adrenergic presynaptic endings. With this low level of presynaptic stimulation, quantal currents could be resolved. This occurs at chemical synapses when neurotransmitters are released from the presynaptic neuron and produce excitation or inhibition of the postsynaptic cell. Molecular features of the phasic and tonic presynaptic nerve terminals are currently under investigation. The toxin irreversibly binds to presynaptic cholinergic receptors at motor nerve terminals and is subsequently internalized. A variety of experiments indicate that single synaptic connections exhibit a broad distribution of presynaptic release probabilities. From a screen of 24,000 mutagenized flies, 17 mutants with presynaptic defects in synaptic transmission were recovered. In presynaptic inhibition, synapses are temporarily ‘decommissioned’ to weaken the response; but in other cases, they are added to strengthen it. The stimulants promote the release of dopamine and norepinephrine from presynaptic neurons into the synaptic cleft but then block reuptake by these same neurons. Postsynaptic proteins receive the neurotransmitters released by presynaptic proteins. It does so by blocking the normal presynaptic reuptake, causing an increase in function or activity level of these transmitters. The properties of the presynaptic neuron can also be influenced by the cell with which it makes a synapse. Norepinephrine is a potent vasoconstrictor synthesized from tyrosine in the presynaptic neuron. The release of neurotransmitter is variable and dependent on the properties of the presynaptic terminal.
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