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词汇 excipient
释义

Definition of excipient in English:

excipient

nounɛkˈsɪpɪəntɪkˈsɪpiənt
  • An inactive substance that serves as the vehicle or medium for a drug or other active substance.

    (用作药物载体的)赋形剂

    excipients are things like colouring agents, preservatives, and fillers
    Example sentencesExamples
    • Authenticating pharmaceuticals - raw materials, active pharmaceutical ingredients, excipients, and finished dosage forms - throughout the entire supply chain is essential for maintaining product integrity.
    • Also, both studies used a dosage form that contains a dissolution-inhibiting excipient, magnesium stearate.
    • Analytical methods which will work on undiluted, individual ingredients may not work well on finished products containing other non-herbal ingredients or excipients.
    • It is talking about incompatibilities between the excipients and the active drug as something which should be considered?
    • However, the term ‘drug’ excludes contaminants (such as in herbal medicines) or supposedly inactive excipients in a formulation.
    • Subjects covered in the video included function and rationale for use of excipients, powder sieving and blending, and tablet dedusting/ polishing.
    • They were made this way: the appropriate amount of a solution containing the active ingredient and the excipient or bulking agent was placed in the open vials.
    • Alternately, the drug and its excipients can be made into particles of various sizes.
    • Control cells consisted of untreated cells, cells incubated with the mannitol excipient and exposed to light or cells exposed to the dye alone.
    • Conventional lectures covering the function and rationale of excipients, methods of tablet production, and the physical and analytical tests performed on tablets were provided prior to any intervention.
    • The ‘new’ Nardil contains the same 15 milligrams of phenylzine sulfate/tablet but the excipients have been dramatically altered.
    • The tests showed that the new product can be safely used in serum/animal protein-free cell culture systems, as a pharmaceutical excipient and in drug delivery.
    • Again, this will need to be incorporated into clinical protocols, although it is noted that other photosensitizers and antineoplastic drugs in common use, such as paclitaxol, also use similar excipients.
    • A second investigation revealed that the decrease of bioavailability of R with H was not due to the excipients present in H tablets.
    • Most tablets and some capsules contain fillers, binders, or excipients (substances that help keep the herb dry during manufacturing).

Origin

Early 18th century (as an adjective in the sense 'that takes exception'): from Latin excipient- 'taking out', from the verb excipere.

Definition of excipient in US English:

excipient

nounikˈsipēəntɪkˈsɪpiənt
  • An inactive substance that serves as the vehicle or medium for a drug or other active substance.

    (用作药物载体的)赋形剂

    excipients are things like coloring agents, preservatives, and fillers
    Example sentencesExamples
    • They were made this way: the appropriate amount of a solution containing the active ingredient and the excipient or bulking agent was placed in the open vials.
    • Most tablets and some capsules contain fillers, binders, or excipients (substances that help keep the herb dry during manufacturing).
    • Authenticating pharmaceuticals - raw materials, active pharmaceutical ingredients, excipients, and finished dosage forms - throughout the entire supply chain is essential for maintaining product integrity.
    • Conventional lectures covering the function and rationale of excipients, methods of tablet production, and the physical and analytical tests performed on tablets were provided prior to any intervention.
    • Analytical methods which will work on undiluted, individual ingredients may not work well on finished products containing other non-herbal ingredients or excipients.
    • It is talking about incompatibilities between the excipients and the active drug as something which should be considered?
    • The tests showed that the new product can be safely used in serum/animal protein-free cell culture systems, as a pharmaceutical excipient and in drug delivery.
    • Alternately, the drug and its excipients can be made into particles of various sizes.
    • Subjects covered in the video included function and rationale for use of excipients, powder sieving and blending, and tablet dedusting/ polishing.
    • The ‘new’ Nardil contains the same 15 milligrams of phenylzine sulfate/tablet but the excipients have been dramatically altered.
    • However, the term ‘drug’ excludes contaminants (such as in herbal medicines) or supposedly inactive excipients in a formulation.
    • Also, both studies used a dosage form that contains a dissolution-inhibiting excipient, magnesium stearate.
    • Control cells consisted of untreated cells, cells incubated with the mannitol excipient and exposed to light or cells exposed to the dye alone.
    • A second investigation revealed that the decrease of bioavailability of R with H was not due to the excipients present in H tablets.
    • Again, this will need to be incorporated into clinical protocols, although it is noted that other photosensitizers and antineoplastic drugs in common use, such as paclitaxol, also use similar excipients.

Origin

Early 18th century (as an adjective in the sense ‘that takes exception’): from Latin excipient- ‘taking out’, from the verb excipere.

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