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词汇 muscimol
释义

Definition of muscimol in English:

muscimol

noun ˈmʌskɪmɒl
mass nounChemistry
  • A narcotic and hallucinogenic compound found in the fly agaric and other fungi.

    〔化〕毒蝇蕈醇,氨甲基羟异噁唑

    An alkaloid related to oxazole; chemical formula: C₄H₆N₂O₂

    Example sentencesExamples
    • Microinjections of muscimol and bicuculline into the pontine reticular formation modify the sleep-waking cycle in the rat.
    • The administration of muscimol inhibited the development of reverse tolerance against morphine hyperactivity in mice that had received chronic administration of morphine.
    • Eugster and Waser first isolated muscimol from this species and it is this substance which is the main hallucinogen.
    • Indeed, benzodiazepines can interact with other neurotransmitters within the DPAG and, compared to muscimol, can exert different actions on heterogeneous GABAA receptor subtypes.
    • The substances were GABA, a GABA-enhancing compound called muscimol, and a GABA-blocking compound called bicuculline.

Origin

1960s: from modern Latin muscaria (see muscarine) + im(ine) + -ol.

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