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词汇 nalidixic acid
释义

Definition of nalidixic acid in English:

nalidixic acid

nounˌnalɪˈdɪksɪkˌnāliˌdiksik ˈasid
mass nounMedicine
  • A synthetic compound which inhibits the multiplication of bacteria, used chiefly to treat urinary infections.

    〔医〕萘啶酸,萘啶酮酸

    A heterocyclic compound; chemical formula: C₁₂H₁₂N₂O₃

    Example sentencesExamples
    • There was no association between nalidixic acid and chloramphenicol susceptibility.
    • There has also been a change in the antimicrobial susceptibility pattern; resistance to ampicillin and nalidixic acid has changed in recent times.
    • In India, almost 100% of the healthy population carry bacteria that are resistant to ampicillin, trimethoprim, nalidixic acid, and chloramphenicol.
    • The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).
    • The organism isolated was resistant to ampicillin, cotrimoxazole, nalidixic acid and norfloxacin.

Origin

1960s: nalidixic by rearrangement of elements from naphthalene, carboxylic, and di-1 (forming the systematic name).

Definition of nalidixic acid in US English:

nalidixic acid

nounˌnāliˌdiksik ˈasid
Medicine
  • A synthetic compound which inhibits the multiplication of bacteria, used chiefly to treat urinary infections.

    〔医〕萘啶酸,萘啶酮酸

    A heterocyclic compound; chemical formula: C₁₂H₁₂N₂O₃

    Example sentencesExamples
    • The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).
    • The organism isolated was resistant to ampicillin, cotrimoxazole, nalidixic acid and norfloxacin.
    • There was no association between nalidixic acid and chloramphenicol susceptibility.
    • In India, almost 100% of the healthy population carry bacteria that are resistant to ampicillin, trimethoprim, nalidixic acid, and chloramphenicol.
    • There has also been a change in the antimicrobial susceptibility pattern; resistance to ampicillin and nalidixic acid has changed in recent times.

Origin

1960s: nalidixic by rearrangement of elements from naphthalene, carboxylic, and di- (forming the systematic name).

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