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词汇 naltrexone
释义

Definition of naltrexone in English:

naltrexone

noun nalˈtrɛksəʊnnalˈtreksōn
mass nounMedicine
  • A synthetic drug, similar to morphine, which blocks opiate receptors in the nervous system and is used chiefly in the treatment of heroin addiction.

    〔医〕纳曲酮

    Example sentencesExamples
    • Long-term opioid therapy for chronic pain or heroin dependence is a contraindication for naltrexone because the drug could precipitate severe withdrawal syndrome.
    • It is working on a version containing naltrexone, an opiate antagonist that would block oxycodone's euphoric effects once the pill was crushed.
    • Small studies have suggested that the opiate antagonist naltrexone is effective as an adjuvant therapy for treating alcohol addiction.
    • The use of the opiate antagonist, naltrexone in the treatment of autism is reasonable since it antagonizes endogenous opiate receptor activity.
    • Thus, the researchers proposed the hypothesis that alcohol releases endogenous opioids and that naltrexone blocks the opioid receptor.
    • In addition, this research group also determined that naloxone, an opiate antagonist similar to naltrexone, prevented the action of both marijuana and heroin on dopamine transmission.

Origin

1970s: from a contraction of N-al(lylnoroxymorph)one (see naloxone), with the insertion of the arbitrary element -trex-.

Definition of naltrexone in US English:

naltrexone

nounnalˈtreksōn
Medicine
  • A synthetic drug, similar to morphine, which blocks opiate receptors in the nervous system and is used chiefly in the treatment of heroin addiction.

    〔医〕纳曲酮

    Example sentencesExamples
    • Thus, the researchers proposed the hypothesis that alcohol releases endogenous opioids and that naltrexone blocks the opioid receptor.
    • In addition, this research group also determined that naloxone, an opiate antagonist similar to naltrexone, prevented the action of both marijuana and heroin on dopamine transmission.
    • The use of the opiate antagonist, naltrexone in the treatment of autism is reasonable since it antagonizes endogenous opiate receptor activity.
    • Small studies have suggested that the opiate antagonist naltrexone is effective as an adjuvant therapy for treating alcohol addiction.
    • Long-term opioid therapy for chronic pain or heroin dependence is a contraindication for naltrexone because the drug could precipitate severe withdrawal syndrome.
    • It is working on a version containing naltrexone, an opiate antagonist that would block oxycodone's euphoric effects once the pill was crushed.

Origin

1970s: from a contraction of N-al(lylnoroxymorph)one (see naloxone), with the insertion of the arbitrary element -trex-.

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