Definition of probenecid in English:

probenecid

noun prəʊˈbɛnɪsɪdprōˈbenəsəd

mass nounMedicine

A synthetic sulphur-containing compound which promotes increased excretion of uric acid and is used to treat gout.
〔医〕对二丙磺胺氨基苯甲酸，丙黄舒，羧苯磺胺
Example sentencesExamples
- Administration of this drug with probenecid should be avoided as it has been found to inhibit the renal excretion of meropenem.
- To decrease the potential for nephrotoxicity, coadministration of probenecid and hydration with 0.9% sodium chloride is required.
- There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production.
- Scientists found that a simple benzoic acid derivative called probenecid stops many drugs, including antibiotics, being removed from the blood by the kidneys.
- Parenteral treatment refused: amoxycillin 500 mg four times a day plus probenecid 500 mg four times a day for 14 days

Origin

1950s: from pro(pyl) + ben(zoic) + -e- + (a)cid.

Definition of probenecid in US English:

probenecid

nounprōˈbenəsəd

Medicine

A synthetic compound that promotes increased excretion of uric acid and is used to treat gout.
〔医〕对二丙磺胺氨基苯甲酸，丙黄舒，羧苯磺胺
Chemical formula C₁₃H₁₉NO₄S
Example sentencesExamples
- There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production.
- Scientists found that a simple benzoic acid derivative called probenecid stops many drugs, including antibiotics, being removed from the blood by the kidneys.
- To decrease the potential for nephrotoxicity, coadministration of probenecid and hydration with 0.9% sodium chloride is required.
- Administration of this drug with probenecid should be avoided as it has been found to inhibit the renal excretion of meropenem.
- Parenteral treatment refused: amoxycillin 500 mg four times a day plus probenecid 500 mg four times a day for 14 days

Origin

1950s: from pro(pyl) + ben(zoic) + -e- + (a)cid.

词汇	probenecid
释义	Definition of probenecid in English: probenecid noun prəʊˈbɛnɪsɪdprōˈbenəsəd mass nounMedicine A synthetic sulphur-containing compound which promotes increased excretion of uric acid and is used to treat gout. 〔医〕对二丙磺胺氨基苯甲酸，丙黄舒，羧苯磺胺 Example sentencesExamples Administration of this drug with probenecid should be avoided as it has been found to inhibit the renal excretion of meropenem. To decrease the potential for nephrotoxicity, coadministration of probenecid and hydration with 0.9% sodium chloride is required. There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production. Scientists found that a simple benzoic acid derivative called probenecid stops many drugs, including antibiotics, being removed from the blood by the kidneys. Parenteral treatment refused: amoxycillin 500 mg four times a day plus probenecid 500 mg four times a day for 14 days Origin 1950s: from pro(pyl) + ben(zoic) + -e- + (a)cid. Definition of probenecid in US English: probenecid nounprōˈbenəsəd Medicine A synthetic compound that promotes increased excretion of uric acid and is used to treat gout. 〔医〕对二丙磺胺氨基苯甲酸，丙黄舒，羧苯磺胺 Chemical formula C₁₃H₁₉NO₄S Example sentencesExamples There are two classes of drugs to reduce uric acid: uricosurics, such as probenecid, which increases excretion, and xanthine oxidase inhibitors, such as allopurinol, which reduce production. Scientists found that a simple benzoic acid derivative called probenecid stops many drugs, including antibiotics, being removed from the blood by the kidneys. To decrease the potential for nephrotoxicity, coadministration of probenecid and hydration with 0.9% sodium chloride is required. Administration of this drug with probenecid should be avoided as it has been found to inhibit the renal excretion of meropenem. Parenteral treatment refused: amoxycillin 500 mg four times a day plus probenecid 500 mg four times a day for 14 days Origin 1950s: from pro(pyl) + ben(zoic) + -e- + (a)cid.
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