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词汇 fibrin
释义

Definition of fibrin in English:

fibrin

noun ˈfʌɪbrɪnˈfɪbrɪnˈfaɪbrən
mass nounBiochemistry
  • An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.

    〔生化〕血纤蛋白,纤维蛋白

    Example sentencesExamples
    • Each microvillus contains a core of actin filaments organized in bundles by actin binding proteins such as villin, fibrin, and espin.
    • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.
    • In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
    • All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis.
    • It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.

Derivatives

  • fibrinoid

  • adjective
    Biochemistry
    • In some areas, particularly those close to the surface of the tumors, the eosinophilic extracellular material resembled fibrinoid necrosis and showed associated areas of organization consistent with typical granulation tissue.
      Example sentencesExamples
      • Fibrin deposition was found in areas of fibrinoid necrosis within the glomeruli and in the interstitium.
      • Other nonspecific features include intimal proliferation, duplication and/or fragmentation of the internal elastic lamina, a sparse perivascular inflammatory infiltrate, and fibrinoid necrosis of the intima.
      • Delayed radiation injuries result in increased tissue pressure from oedema, vascular injury leading to infarction, damage to endothelial cells and fibrinoid necrosis of small arteries and arterioles.
      • In addition, three patients had hyaline collagen degeneration, four myxoid degeneration, three fibrinoid degeneration, and six had mixed lesions.
  • fibrinous

  • adjective ˈfʌɪbrɪnəsˈfɪbrɪnəsˈfaɪbrənəs
    Biochemistry
    • This progressive process involves alterations in fibrin turnover, which leads to the formation of fibrinous deposits and membranes with sequestration of infected fluid.
      Example sentencesExamples
      • Upon review of the slides, we observed a fragment of bladder mucosa with dilated vascular spaces, hemorrhage, acute inflammation, fibrinous exudate, and focal fibrosis in the lamina propria.
      • During a period of hours, the gauze dries on the wound bed and adheres to the range of tissues in it, including beefy red granulation tissue, yellow fibrinous tissue, or black necrotic tissue.
      • He later presented with cardiomyopathy with severe aortic insufficiency due to the destruction of the aortic valve prosthesis by sterile fibrinous vegetation.
      • Because the heart is constricted by fluid or a rigid fibrinous or calcified pericardium, negative intrathoracic pressure during inspiration is not transmitted to the pericardial sac.

Origin

Early 19th century: from fibre + -in1.

Definition of fibrin in US English:

fibrin

nounˈfībrənˈfaɪbrən
Biochemistry
  • An insoluble protein formed from fibrinogen during the clotting of blood. It forms a fibrous mesh that impedes the flow of blood.

    〔生化〕血纤蛋白,纤维蛋白

    Example sentencesExamples
    • In the assay, the addition of thrombin to citrated plasma causes the conversion of fibrinogen to fibrin, yielding a stops bleeding much quicker.
    • Each microvillus contains a core of actin filaments organized in bundles by actin binding proteins such as villin, fibrin, and espin.
    • It converts fibrinogen to fibrin, and unlike thrombin, is unaffected by heparin.
    • All of these agents convert plasminogen to plasmin, which in turn breaks down fibrin and promotes clot lysis.
    • Plasminogen binds to both fibrinogen and fibrin, thereby being incorporated into a clot as it is formed.

Origin

Early 19th century: from fiber + -in.

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