Definition of kinetochore in English:

kinetochore

nounkʌɪˈniːtəʊkɔːkɪˈniːtəʊkɔːkəˈnetəˌkôr

Biology

1A complex of proteins associated with the centromere of a chromosome during cell division, to which the microtubules of the spindle attach.
Example sentencesExamples
- A second checkpoint pathway, the spindle checkpoint, operates at a similar point in meiosis, preventing progression into anaphase if the spindle apparatus fails to connect appropriately with kinetochores.
- In metaphase, sister kinetochores attach to microtubules emanating from opposite spindle pole bodies during alignment of the chromosomes.
- Chromosome loss may be the result of either non-attachment of the chromosome kinetochore to the spindle microtubules or chromosome lagging at anaphase and gives rise to a micronucleus.
- The DNA is asymmetrically distributed to the daughter cells when the kinetochores do not attach and the spindle checkpoint does not restrain mitosis.
- This cohesion or ‘chiasma binder’ function ensures the generation of a bipolar spindle in which tension is generated at the kinetochores.
1. 1.1historical
  another term for centromere

Origin

1930s: from kineto- 'of movement' + Greek khōros 'place'.

Definition of kinetochore in US English:

kinetochore

nounkəˈnetəˌkôr

Biology

1A complex of proteins associated with the centromere of a chromosome during cell division, to which the microtubules of the spindle attach.
Example sentencesExamples
- In metaphase, sister kinetochores attach to microtubules emanating from opposite spindle pole bodies during alignment of the chromosomes.
- The DNA is asymmetrically distributed to the daughter cells when the kinetochores do not attach and the spindle checkpoint does not restrain mitosis.
- A second checkpoint pathway, the spindle checkpoint, operates at a similar point in meiosis, preventing progression into anaphase if the spindle apparatus fails to connect appropriately with kinetochores.
- Chromosome loss may be the result of either non-attachment of the chromosome kinetochore to the spindle microtubules or chromosome lagging at anaphase and gives rise to a micronucleus.
- This cohesion or ‘chiasma binder’ function ensures the generation of a bipolar spindle in which tension is generated at the kinetochores.
1. 1.1historical
  another term for centromere

Origin

1930s: from kineto- ‘of movement’ + Greek khōros ‘place’.

词汇	kinetochore
释义	Definition of kinetochore in English: kinetochore nounkʌɪˈniːtəʊkɔːkɪˈniːtəʊkɔːkəˈnetəˌkôr Biology 1A complex of proteins associated with the centromere of a chromosome during cell division, to which the microtubules of the spindle attach. Example sentencesExamples A second checkpoint pathway, the spindle checkpoint, operates at a similar point in meiosis, preventing progression into anaphase if the spindle apparatus fails to connect appropriately with kinetochores. In metaphase, sister kinetochores attach to microtubules emanating from opposite spindle pole bodies during alignment of the chromosomes. Chromosome loss may be the result of either non-attachment of the chromosome kinetochore to the spindle microtubules or chromosome lagging at anaphase and gives rise to a micronucleus. The DNA is asymmetrically distributed to the daughter cells when the kinetochores do not attach and the spindle checkpoint does not restrain mitosis. This cohesion or ‘chiasma binder’ function ensures the generation of a bipolar spindle in which tension is generated at the kinetochores. 1.1historical another term for centromere Origin 1930s: from kineto- 'of movement' + Greek khōros 'place'. Definition of kinetochore in US English: kinetochore nounkəˈnetəˌkôr Biology 1A complex of proteins associated with the centromere of a chromosome during cell division, to which the microtubules of the spindle attach. Example sentencesExamples In metaphase, sister kinetochores attach to microtubules emanating from opposite spindle pole bodies during alignment of the chromosomes. The DNA is asymmetrically distributed to the daughter cells when the kinetochores do not attach and the spindle checkpoint does not restrain mitosis. A second checkpoint pathway, the spindle checkpoint, operates at a similar point in meiosis, preventing progression into anaphase if the spindle apparatus fails to connect appropriately with kinetochores. Chromosome loss may be the result of either non-attachment of the chromosome kinetochore to the spindle microtubules or chromosome lagging at anaphase and gives rise to a micronucleus. This cohesion or ‘chiasma binder’ function ensures the generation of a bipolar spindle in which tension is generated at the kinetochores. 1.1historical another term for centromere Origin 1930s: from kineto- ‘of movement’ + Greek khōros ‘place’.
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