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词汇 Klinefelter's syndrome
释义

Definition of Klinefelter's syndrome in English:

Klinefelter's syndrome

nounˈklʌɪnˌfɛltəzˈklīnˌfeltərz ˌsindrōm
mass nounMedicine
  • A syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts.

    〔医〕克莱恩费尔特氏综合征(一种影响男性的综合征,患者体内细胞中除正常的XY染色体外,多出一个X染色体,其特征为体形高而瘦削,睾丸小,不能生育,乳房扩大)

    Example sentencesExamples
    • Men born with a genetic disorder called Klinefelter's syndrome often develop gynecomastia, as do males with adrenal tumors and liver disease.
    • Risk factors for breast cancer in men suggest a hormonal imbalance, and up to 20 percent of male breast cancer cases have been associated with Klinefelter's syndrome.
    • It is associated with breast and testicular abnormalities, infertility and Klinefelter's syndrome, a genetic abnormality in which men have one or more extra X chromosomes.
    • For example, a screening check of Down's Syndrome might pick up the extra X chromosome that occurs in Chris's condition, Klinefelter's syndrome.
    • In Klinefelter's syndrome, for instance, the presence of several X chromosomes and one Y chromosome sometimes results in sexual ‘ambiguity’.

Origin

1940s: named after Harry F. Klinefelter (born 1912), American physician.

Definition of Klinefelter's syndrome in US English:

Klinefelter's syndrome

nounˈklīnˌfeltərz ˌsindrōm
Medicine
  • A syndrome affecting males in which the cells have an extra X chromosome (in addition to the normal XY), characterized by a tall thin physique, small infertile testes, and enlarged breasts.

    〔医〕克莱恩费尔特氏综合征(一种影响男性的综合征,患者体内细胞中除正常的XY染色体外,多出一个X染色体,其特征为体形高而瘦削,睾丸小,不能生育,乳房扩大)

    Example sentencesExamples
    • In Klinefelter's syndrome, for instance, the presence of several X chromosomes and one Y chromosome sometimes results in sexual ‘ambiguity’.
    • Risk factors for breast cancer in men suggest a hormonal imbalance, and up to 20 percent of male breast cancer cases have been associated with Klinefelter's syndrome.
    • Men born with a genetic disorder called Klinefelter's syndrome often develop gynecomastia, as do males with adrenal tumors and liver disease.
    • It is associated with breast and testicular abnormalities, infertility and Klinefelter's syndrome, a genetic abnormality in which men have one or more extra X chromosomes.
    • For example, a screening check of Down's Syndrome might pick up the extra X chromosome that occurs in Chris's condition, Klinefelter's syndrome.

Origin

1940s: named after Harry F. Klinefelter (born 1912), American physician.

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