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词汇 necrobiosis
释义

Definition of necrobiosis in English:

necrobiosis

noun ˌnɛkrə(ʊ)bʌɪˈəʊsɪsˌnekrəbīˈōsəs
mass nounMedicine
  • Gradual degeneration and death of cells in the body tissues.

    〔医〕渐进性(细胞)坏死

    Example sentencesExamples
    • Apart from necrobiosis lipoidica, diabetes is not a primary cause of ulceration but often leads to ulceration through neuropathy or ischaemia, or both.
    • Ulceration occurs in about one third of diabetic patients with necrobiosis lipoidica, and spontaneous remission is relatively uncommon.
    • Diabetic necrobiosis typically causes discrete pretibial plaques, not the confluent skin changes seen in this patient.
    • There are multiple other reports of silk suture-induced foreign-body reactions causing significant necrobiosis.
    • Three common skin disorders seen in patients with diabetes are diabetic dermopathy, necrobiosis lipoidica diabeticorum, and bullous diabeticorum.

Derivatives

  • necrobiotic

  • adjective ˌnɛkrə(ʊ)bʌɪˈɒtɪk
    Medicine
    • The authors describe an adverse localized cutaneous reaction caused by the injection of disodium clodronate, histologically presenting as a necrobiotic palisading granuloma.
      Example sentencesExamples
      • Histopathologic examination of the tissue showed a necrobiotic granuloma with associated histiocytic infiltration.
      • Because necrobiotic nodules may be indistinguishable radiologically from carcinoma and infectious granulomas, it has been recommended that all pulmonary nodules in rheumatoid patients be biopsied.
      • Despite the increased frequency of lung cancer in patients with rheumatoid lung disease, we could find only 2 previous case reports of a carcinoma occurring in intimate association with a necrobiotic nodule.
      • Due to the absence of hyaline necrobiosis, a diagnosis of necrobiotic xanthogranuloma was therefore made.
      • Acinar cells surrounding the necrotic foci showed atrophy and necrobiotic changes, and numerous eosinophilic intranuclear inclusions with clear halos (Cowdry type A) were noted.
      • A diagnosis of necrobiotic xanthogranuloma was established.
      • Central necrobiotic area contains abundant connective tissue mucins which is lightly basophilic in appearance.

Origin

Mid 19th century: from necro- + Greek biōsis ‘mode of life’ (from bios ‘life’).

Definition of necrobiosis in US English:

necrobiosis

nounˌnekrəbīˈōsəs
Medicine
  • Gradual degeneration and death of cells in the body tissues.

    〔医〕渐进性(细胞)坏死

    Example sentencesExamples
    • There are multiple other reports of silk suture-induced foreign-body reactions causing significant necrobiosis.
    • Three common skin disorders seen in patients with diabetes are diabetic dermopathy, necrobiosis lipoidica diabeticorum, and bullous diabeticorum.
    • Diabetic necrobiosis typically causes discrete pretibial plaques, not the confluent skin changes seen in this patient.
    • Apart from necrobiosis lipoidica, diabetes is not a primary cause of ulceration but often leads to ulceration through neuropathy or ischaemia, or both.
    • Ulceration occurs in about one third of diabetic patients with necrobiosis lipoidica, and spontaneous remission is relatively uncommon.

Origin

Mid 19th century: from necro- + Greek biōsis ‘mode of life’ (from bios ‘life’).

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