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词汇 proinsulin
释义

Definition of proinsulin in English:

proinsulin

nounprəʊˈɪnsjʊlɪnprōˈinsələn
mass nounBiochemistry
  • A substance produced by the pancreas which is converted to insulin.

    〔生化〕胰岛素原

    Example sentencesExamples
    • The processing of proinsulin to insulin within the secretory granules of the Golgi complex is dependent on critical levels of pH as well as ATP.
    • Following cleavage of the 24 amino acid signal peptide the protein folds into proinsulin.
    • Insulin is synthesized as a precursor, preproinsulin, and after removal of the signal peptide, proinsulin folds to form the correct tertiary structure.
    • Unlike the single chain precursor of insulin, proinsulin, this new construct retains up to 40 per cent of insulin activity.
    • Insulin-like growth factor 1 is a peptide structurally related to proinsulin and has a primary role in promoting skeletal muscle differentiation and growth.

Definition of proinsulin in US English:

proinsulin

nounprōˈinsələn
Biochemistry
  • A substance produced by the pancreas which is converted to insulin.

    〔生化〕胰岛素原

    Example sentencesExamples
    • Insulin is synthesized as a precursor, preproinsulin, and after removal of the signal peptide, proinsulin folds to form the correct tertiary structure.
    • Unlike the single chain precursor of insulin, proinsulin, this new construct retains up to 40 per cent of insulin activity.
    • Following cleavage of the 24 amino acid signal peptide the protein folds into proinsulin.
    • The processing of proinsulin to insulin within the secretory granules of the Golgi complex is dependent on critical levels of pH as well as ATP.
    • Insulin-like growth factor 1 is a peptide structurally related to proinsulin and has a primary role in promoting skeletal muscle differentiation and growth.
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