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词汇 nephrotoxic
释义

Definition of nephrotoxic in English:

nephrotoxic

adjective ˌnɛfrə(ʊ)ˈtɒksɪkˌnefrəˈtäksik
  • Damaging or destructive to the kidneys.

    肾中毒的

    Example sentencesExamples
    • Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins.
    • The common potentially reversible causes are sepsis, excessive diuresis or paracentesis, and nephrotoxic drugs.
    • Patients treated with nephrotoxic medications are at greater risk of developing renal failure.
    • Synergistic toxicity is generally thought to occur when concomitant nephrotoxic drugs are used.
    • Several other drugs used in CF care have nephrotoxic and ototoxic potential.

Derivatives

  • nephrotoxicity

  • noun
    • A multivariate analysis could not correlate nephrotoxicity with the dosing regimen.
      Example sentencesExamples
      • Most of the rare reports of ototoxicity or nephrotoxicity in patients receiving vancomycin are complicated by concomitant illness or drug use associated with such side effects.
      • Use of these materials may decrease reactions such as nausea, flushing and bradycardia, but there is no apparent reduction of anaphylactic reactions or nephrotoxicity.
      • Nearly 40% of the patients had a creatinine clearance below normal, although there was no overt chronic nephrotoxicity.
      • When examining the relationships between peak and trough vancomycin serum levels and the subsequent development of nephrotoxicity or ototoxicity, it is difficult to predict risk based on these data.
  • nephrotoxin

  • noun
    • Management includes correction of fluid and electrolyte levels; avoidance of nephrotoxins; and kidney replacement therapy, when appropriate.
      Example sentencesExamples
      • Acute tubular necrosis may be prevented by promptly treating patients with reversible causes of ischemic or prerenal acute renal failure and by maintaining appropriate hydration in patients who are receiving nephrotoxins.
      • Conditions that place patients at risk for this condition include untreated prerenal azotemia and the use of nephrotoxic drugs or exposure to other nephrotoxins.
      • Though it is a very popular drug, acetaminophen is a nephrotoxin, implicated in thousands of hospitalizations each year.
      • Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins.

Definition of nephrotoxic in US English:

nephrotoxic

adjectiveˌnefrəˈtäksik
  • Damaging or destructive to the kidneys.

    肾中毒的

    Example sentencesExamples
    • Patients treated with nephrotoxic medications are at greater risk of developing renal failure.
    • Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins.
    • The common potentially reversible causes are sepsis, excessive diuresis or paracentesis, and nephrotoxic drugs.
    • Several other drugs used in CF care have nephrotoxic and ototoxic potential.
    • Synergistic toxicity is generally thought to occur when concomitant nephrotoxic drugs are used.
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