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词汇 pronucleus
释义

Definition of pronucleus in English:

pronucleus

nounPlural pronuclei prəʊˈnjuːklɪəsprōˈn(y)o͞oklēəs
Biology
  • Either of a pair of gametic nuclei, in the stage following meiosis but before their fusion leads to the formation of the nucleus of the zygote.

    〔生〕原核,(成熟的卵或精子的)前核

    Example sentencesExamples
    • In normal fertilisation the formation of male and female pronuclei is an important stage just before the maternal and paternal chromosomes start to pair up in preparation for the first cell division.
    • For instance, the migration of the male pronucleus within the animal oocyte after fertilization, together with movements of the female pronucleus, are essential events for nuclear fusion.
    • Meiotic spindle poles of mutant embryos are not as well focused as wild type, and meiotic failure often leads to multiple maternal pronuclei as compared to wild type.
    • Diploid zygotes created by combining a male and a female pronucleus gave rise to viable embryos, but combining two male or two female pronuclei did not.
    • The sperm and egg pronuclei form the zygotic nucleus.

Derivatives

  • pronuclear

  • adjective prəʊˈnjuːklɪəproʊˈn(j)ukliər
    Biology
    • Relating to either of a pair of gametic nuclei, in the stage following meiosis but before their fusion leads to the formation of the nucleus of the zygote.

      〔生〕原核,(成熟的卵或精子的)前核

      gene modifications via pronuclear injection of mouse embryos
      Example sentencesExamples
      • In contrast, wisp embryos arrest after completion of meiosis II, before pronuclear fusion.
      • Arrowheads point to sister chromatids and refer to chromosome replication during the pronuclear stage.
      • In mice and humans, the pronuclear membranes disappear before the pronuclei come together.

Definition of pronucleus in US English:

pronucleus

nounprōˈn(y)o͞oklēəs
Biology
  • Either of a pair of gametic nuclei, in the stage following meiosis but before their fusion leads to the formation of the nucleus of the zygote.

    〔生〕原核,(成熟的卵或精子的)前核

    Example sentencesExamples
    • Diploid zygotes created by combining a male and a female pronucleus gave rise to viable embryos, but combining two male or two female pronuclei did not.
    • The sperm and egg pronuclei form the zygotic nucleus.
    • For instance, the migration of the male pronucleus within the animal oocyte after fertilization, together with movements of the female pronucleus, are essential events for nuclear fusion.
    • Meiotic spindle poles of mutant embryos are not as well focused as wild type, and meiotic failure often leads to multiple maternal pronuclei as compared to wild type.
    • In normal fertilisation the formation of male and female pronuclei is an important stage just before the maternal and paternal chromosomes start to pair up in preparation for the first cell division.
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