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词汇 phagosome
释义

Definition of phagosome in English:

phagosome

noun ˈfaɡə(ʊ)səʊmˈfaɡəˌsōm
Biology
  • A vacuole in the cytoplasm of a cell, containing a phagocytosed particle enclosed within a part of the cell membrane.

    〔生〕吞噬体

    Example sentencesExamples
    • The process of phagocytosis continues until the bacterium is completely internalized, surrounded by membrane in the phagosome.
    • We developed a method for simultaneous measurement of average extra- and intracellular oxygen concentrations, which also does not require the presence of phagosomes and therefore can be used in any cell line.
    • In the phagosomes, lysosomes are activated and fuse with the apoptotic bodies, bringing on their dissolution.
    • After internalization of organisms into phagosomes, secondary lysosomes are fused to form the complete parasitophorus vacuole.
    • The researchers engineer a BCG strain that secretes the listeriolysin protein, which punches holes in the membranes of phagosomes where M. tuberculosis is located, allowing better T cell-mediated immunity.

Derivatives

  • phagosomal

  • adjective
    Biology
    • Failure of mycobacteria to survive in the absence of specific iron uptake system suggests the scarcity of this important nutrient in phagosomal environment 59.
      Example sentencesExamples
      • We next analysed phagosomal pH in wild-type and Rab27a-deficient dendritic cells.
      • The pathogenesis of mycobacterial infection is associated with an ability to interfere with maturation of the phagosomal compartment after ingestion by macrophages.
      • Electrons are transferred from cytoplasmic NADPH to oxygen on the phagosomal side of the membrane, generating the so-called reactive oxygen species, e.g., superoxide, hydrogen peroxide, hydroxyl radical, and singlet oxygen.
      • The lack of urease C allows phagosomal acidification and provides an ideal pH environment for listeriolysin.

Definition of phagosome in US English:

phagosome

nounˈfaɡəˌsōm
Biology
  • A vacuole in the cytoplasm of a cell, containing a phagocytosed particle enclosed within a part of the cell membrane.

    〔生〕吞噬体

    Example sentencesExamples
    • We developed a method for simultaneous measurement of average extra- and intracellular oxygen concentrations, which also does not require the presence of phagosomes and therefore can be used in any cell line.
    • The researchers engineer a BCG strain that secretes the listeriolysin protein, which punches holes in the membranes of phagosomes where M. tuberculosis is located, allowing better T cell-mediated immunity.
    • The process of phagocytosis continues until the bacterium is completely internalized, surrounded by membrane in the phagosome.
    • In the phagosomes, lysosomes are activated and fuse with the apoptotic bodies, bringing on their dissolution.
    • After internalization of organisms into phagosomes, secondary lysosomes are fused to form the complete parasitophorus vacuole.
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