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词汇 phosphodiesterase
释义

Definition of phosphodiesterase in English:

phosphodiesterase

noun ˌfɒsfə(ʊ)dʌɪˈɛstəreɪzˌfäsfōdīˈestərās
mass nounBiochemistry
  • An enzyme which breaks a phosphodiester bond in an oligonucleotide.

    〔生化〕磷酸二酯酶

    Example sentencesExamples
    • Calf spleen phosphodiesterase, snake venom phosphodiesterase and alkaline phosphatase were from Roche Molecular Biochemicals (Meylan, France).
    • One technique involves using drugs, such as a growth hormone, to activate a molecule known as ERK5, which suppresses the enzyme phosphodiesterase.
    • Cilostazol blocks the activity of the enzyme phosphodiesterase which induces platelet aggregation and prevents the degradation of cyclic adenosine monophosphate (cAMP).
    • In isolated cilia and in intact olfactory receptor neurons, studies have shown basal activities of both adenylate cyclase and cAMP phosphodiesterase.
    • Its mechanism of action is thought to involve inhibition of cyclic adenosine monophosphate phosphodiesterase and enhancement of the effect of prostaglandin I2.

Definition of phosphodiesterase in US English:

phosphodiesterase

nounˌfäsfōdīˈestərās
Biochemistry
  • An enzyme which breaks a phosphodiester bond in an oligonucleotide.

    〔生化〕磷酸二酯酶

    Example sentencesExamples
    • In isolated cilia and in intact olfactory receptor neurons, studies have shown basal activities of both adenylate cyclase and cAMP phosphodiesterase.
    • Calf spleen phosphodiesterase, snake venom phosphodiesterase and alkaline phosphatase were from Roche Molecular Biochemicals (Meylan, France).
    • One technique involves using drugs, such as a growth hormone, to activate a molecule known as ERK5, which suppresses the enzyme phosphodiesterase.
    • Cilostazol blocks the activity of the enzyme phosphodiesterase which induces platelet aggregation and prevents the degradation of cyclic adenosine monophosphate (cAMP).
    • Its mechanism of action is thought to involve inhibition of cyclic adenosine monophosphate phosphodiesterase and enhancement of the effect of prostaglandin I2.
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