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词汇 ligand
释义

Definition of ligand in English:

ligand

noun ˈlɪɡ(ə)nd
Chemistry
  • 1An ion or molecule attached to a metal atom by coordinate bonding.

    〔化〕配位体

    Example sentencesExamples
    • Ligand field theory, like crystal field theory, concentrates on what happens when ligands split the central metal atom's inner orbitals.
    • The bonding between the ligand and the metal ion is intermediate between covalent and electrostatic.
    • This binding affinity is related to free enthalpy of the formation of the product of metal and ligand.
    • Furthermore, the molecular arrangement of the three citrate ligands allows the possible introduction of other catalytic metal centres.
    • Special care was taken to include all the hydrogen bonds between the zinc ligands and the surrounding residues.
    1. 1.1Biochemistry A molecule that binds to another (usually larger) molecule.
      〔生化〕配(位)体,配基
      Example sentencesExamples
      • Inside the human body, there are mu, Kappa, and delta opiate receptors, to which the enkephalins and endorphins bind as ligands.
      • Steric clashes between the ligand and protein atoms were alleviated with several minimization cycles in vacuum.
      • They are also biocompatible, and their surfaces can be modified to attach antibodies or other ligands that could be used to target the nanoparticles to specific tissues.
      • It remains to be seen if the surface of the micelle can be used to target macromolecules or ligands of interest, in order to penetrate cells and pinpoint their constituents.
      • Drugs can be encapsulated into or adsorbed onto the particles, along with cell-specific ligands that can home in on a clinical target.

Origin

1950s: from Latin ligandus 'that can be tied', gerundive of ligare 'to bind'.

Rhymes

brigand

Definition of ligand in US English:

ligand

noun
Chemistry
  • 1An ion or molecule attached to a metal atom by coordinate bonding.

    〔化〕配位体

    Example sentencesExamples
    • Special care was taken to include all the hydrogen bonds between the zinc ligands and the surrounding residues.
    • This binding affinity is related to free enthalpy of the formation of the product of metal and ligand.
    • The bonding between the ligand and the metal ion is intermediate between covalent and electrostatic.
    • Ligand field theory, like crystal field theory, concentrates on what happens when ligands split the central metal atom's inner orbitals.
    • Furthermore, the molecular arrangement of the three citrate ligands allows the possible introduction of other catalytic metal centres.
    1. 1.1Biochemistry A molecule that binds to another (usually larger) molecule.
      〔生化〕配(位)体,配基
      Example sentencesExamples
      • It remains to be seen if the surface of the micelle can be used to target macromolecules or ligands of interest, in order to penetrate cells and pinpoint their constituents.
      • They are also biocompatible, and their surfaces can be modified to attach antibodies or other ligands that could be used to target the nanoparticles to specific tissues.
      • Drugs can be encapsulated into or adsorbed onto the particles, along with cell-specific ligands that can home in on a clinical target.
      • Steric clashes between the ligand and protein atoms were alleviated with several minimization cycles in vacuum.
      • Inside the human body, there are mu, Kappa, and delta opiate receptors, to which the enkephalins and endorphins bind as ligands.

Origin

1950s: from Latin ligandus ‘that can be tied’, gerundive of ligare ‘to bind’.

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