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词汇 ligase
释义

Definition of ligase in English:

ligase

noun ˈlɪɡeɪz-ˌɡāz
Biochemistry
  • An enzyme which brings about ligation of DNA or another substance.

    〔生化〕连接酶

    Example sentencesExamples
    • This study shows that in a competition between the two enzymes, DNA ligase trumps the flap endonuclease in capturing bubbles and creating expanded tracts.
    • After all, in nature we can and do observe bacteria using restriction endonucleases and ligases to cut DNA.
    • A number of conjugating enzymes and protein ligases are in the cell, and various combinations confer substrate specificity on the system.
    • These DNA-binding proteins include polymerases, helicases, nucleases, isomerases, ligases, histones, and others.
    • The E.coli bacterium has an enzyme, DNA ligase, which can be used to repair these nicks in the sugar-phosphate backbone of DNA chains to form an intact double-strand.

Origin

1960s: from Latin ligare 'to bind' + -ase.

Definition of ligase in US English:

ligase

noun-ˌɡāz
Biochemistry
  • An enzyme which brings about ligation of DNA or another substance.

    〔生化〕连接酶

    Example sentencesExamples
    • These DNA-binding proteins include polymerases, helicases, nucleases, isomerases, ligases, histones, and others.
    • This study shows that in a competition between the two enzymes, DNA ligase trumps the flap endonuclease in capturing bubbles and creating expanded tracts.
    • A number of conjugating enzymes and protein ligases are in the cell, and various combinations confer substrate specificity on the system.
    • After all, in nature we can and do observe bacteria using restriction endonucleases and ligases to cut DNA.
    • The E.coli bacterium has an enzyme, DNA ligase, which can be used to repair these nicks in the sugar-phosphate backbone of DNA chains to form an intact double-strand.

Origin

1960s: from Latin ligare ‘to bind’ + -ase.

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