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词汇 ganglioside
释义

Definition of ganglioside in English:

ganglioside

noun ˈɡaŋɡlɪə(ʊ)sʌɪdˈɡaNGɡlēəˌsīd
Biochemistry
  • Any of a group of complex lipids which are present in the grey matter of the human brain.

    〔生化〕神经节糖苷

    Example sentencesExamples
    • The condition is due to the absence of an essential enzyme that breaks down a substance called ganglioside, present mainly in the nervous system.
    • We have also clarified the binding specificity of gangliosides with proteins depending on the combination of oligosaccharide chain and protein surface modification.
    • The most complex of these are the gangliosides, which contain one or more sialic acid residues and thus have a net negative change under physiological conditions.
    • There has been strong biochemical evidence that gangliosides are concentrated in these structures.
    • This may be explained by the difference in interaction of the tip with the polar zwitterionic PC headgroups and the anionic oligosaccharide headgroups of the ganglioside.

Origin

1940s: from ganglion + -oside (see -ose2, -ide).

Definition of ganglioside in US English:

ganglioside

nounˈɡaNGɡlēəˌsīd
Biochemistry
  • Any of a group of complex lipids which are present in the gray matter of the human brain.

    〔生化〕神经节糖苷

    Example sentencesExamples
    • The condition is due to the absence of an essential enzyme that breaks down a substance called ganglioside, present mainly in the nervous system.
    • We have also clarified the binding specificity of gangliosides with proteins depending on the combination of oligosaccharide chain and protein surface modification.
    • There has been strong biochemical evidence that gangliosides are concentrated in these structures.
    • The most complex of these are the gangliosides, which contain one or more sialic acid residues and thus have a net negative change under physiological conditions.
    • This may be explained by the difference in interaction of the tip with the polar zwitterionic PC headgroups and the anionic oligosaccharide headgroups of the ganglioside.

Origin

1940s: from ganglion + -oside (see -ose, -ide).

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