Even if myomas from nonpregnant women have pseudopregnant patterns of gene activity, it seems that the impact on cytoplasmic development is blunted in the absence of an overall pregnant type host milieu.
Transgenic mice were generated by pronucleus injection of linearized transgene constructs into fertilized eggs that were subsequently transferred into the oviducts of pseudopregnant foster females.
Blastocyst-stage chimeric embryos were transferred to the uterus of these pseudopregnant females ~ 76 h after hCG injection.
Of the embryos that reached the morula stage, 174 were transplanted into pseudopregnant females, and 27 developed into progeny.
Definition of pseudopregnant in US English:
pseudopregnant
adjective-ˈpreɡnənt
See pseudopregnancy
Example sentencesExamples
Of the embryos that reached the morula stage, 174 were transplanted into pseudopregnant females, and 27 developed into progeny.
Transgenic mice were generated by pronucleus injection of linearized transgene constructs into fertilized eggs that were subsequently transferred into the oviducts of pseudopregnant foster females.
Blastocyst-stage chimeric embryos were transferred to the uterus of these pseudopregnant females ~ 76 h after hCG injection.
Even if myomas from nonpregnant women have pseudopregnant patterns of gene activity, it seems that the impact on cytoplasmic development is blunted in the absence of an overall pregnant type host milieu.