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词汇 Barr body
释义

Definition of Barr body in English:

Barr body

noun bɑːˈbɒdiˈbär ˌbädē
Physiology
  • A small, densely staining structure in the cell nuclei of females, consisting of a condensed, inactive X chromosome. It is regarded as diagnostic of genetic femaleness.

    〔生理〕巴氏小体,性染色质小体

    Example sentencesExamples
    • If the Barr bodies of a normal female were missing, she would exhibit Turners Syndrome.
    • In some tissues, the inactive X chromosome can be identified in the nucleus as a Barr body and X inactivation provides an important model for the inheritance of gene expression.
    • If the child is genetically female then a Barr body should be evident in approximately 10-20 percent of the cells.
    • The formation of Barr bodies is the strategy that humans use for what is called dosage compensation.
    • We now know that the ‘darkly staining’ Barr body is the condensed, inactive X chromosome.

Origin

1960s: named after the Canadian anatomist M. L. Barr (1908–95).

Definition of Barr body in US English:

Barr body

nounˈbär ˌbädē
Physiology
  • A small, densely staining structure in the cell nuclei of female mammals, consisting of a condensed, inactive X chromosome. It is regarded as diagnostic of genetic femaleness.

    〔生理〕巴氏小体,性染色质小体

    Example sentencesExamples
    • The formation of Barr bodies is the strategy that humans use for what is called dosage compensation.
    • In some tissues, the inactive X chromosome can be identified in the nucleus as a Barr body and X inactivation provides an important model for the inheritance of gene expression.
    • If the Barr bodies of a normal female were missing, she would exhibit Turners Syndrome.
    • We now know that the ‘darkly staining’ Barr body is the condensed, inactive X chromosome.
    • If the child is genetically female then a Barr body should be evident in approximately 10-20 percent of the cells.

Origin

1960s: named after the Canadian anatomist M. L. Barr (1908–95).

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