Definition of nucleosome in English:

nucleosome

noun ˈnjuːklɪə(ʊ)səʊmˈn(y)o͞oklēəˌsōm

Biology

A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones.
〔生〕核小体
Example sentencesExamples
- The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation.
- Histones form the core of the nucleosome around which DNA is wrapped.
- DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures.
- Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.
- On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones.

Derivatives

nucleosomal

adjective

Biology

Chromatin is a complex molecular structure composed of nucleosomal repeats in which 147 bp of DNA are wrapped around two copies of the four core histones, H2A, H2B, H3, and H4.
Example sentencesExamples
- Many of these changes are larger in scale than suggested from previous studies and involve a number of DNA-mediated events, including a preference for the removal of a complete turn of nucleosomal DNA.
- The failure to recover mutations in genes encoding nucleosomal histones in this screen may be due to the presence of numerous copies of the histone gene cluster in flies.
- Histones are small basic proteins encoded by a multigene family and are responsible for the nucleosomal organization of chromatin in eukaryotes.
- In wild-type cells, the repressed state spreads unidirectionally through nucleosomal chromatin.

Definition of nucleosome in US English:

nucleosome

nounˈn(y)o͞oklēəˌsōm

Biology

A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones.
〔生〕核小体
Example sentencesExamples
- The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation.
- DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures.
- Histones form the core of the nucleosome around which DNA is wrapped.
- On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones.
- Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.

词汇	nucleosome
释义	Definition of nucleosome in English: nucleosome noun ˈnjuːklɪə(ʊ)səʊmˈn(y)o͞oklēəˌsōm Biology A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. 〔生〕核小体 Example sentencesExamples The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation. Histones form the core of the nucleosome around which DNA is wrapped. DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures. Histone proteins are essential components of nucleosomes in eukaryotic chromosomes. On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones. Derivatives nucleosomal adjective Biology Chromatin is a complex molecular structure composed of nucleosomal repeats in which 147 bp of DNA are wrapped around two copies of the four core histones, H2A, H2B, H3, and H4. Example sentencesExamples Many of these changes are larger in scale than suggested from previous studies and involve a number of DNA-mediated events, including a preference for the removal of a complete turn of nucleosomal DNA. The failure to recover mutations in genes encoding nucleosomal histones in this screen may be due to the presence of numerous copies of the histone gene cluster in flies. Histones are small basic proteins encoded by a multigene family and are responsible for the nucleosomal organization of chromatin in eukaryotes. In wild-type cells, the repressed state spreads unidirectionally through nucleosomal chromatin. Definition of nucleosome in US English: nucleosome nounˈn(y)o͞oklēəˌsōm Biology A structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. 〔生〕核小体 Example sentencesExamples The packaging of DNA with histones into nucleosomes and higher-order chromatin structures has profound effects on transcription initiation. DNA replication, like other DNA-dependent processes, must contend with the organization of DNA into nucleosomes and higher-order chromatin structures. Histones form the core of the nucleosome around which DNA is wrapped. On a molecular level, silenced chromatin consists of specialized heterochromatin proteins and of nucleosomes carrying deacetylated histones. Histone proteins are essential components of nucleosomes in eukaryotic chromosomes.
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