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词汇 macrolide
释义

Definition of macrolide in US English:

macrolide

noun ˈmakrəˌlīdˈmakrəˌlīd
  • Any of a class of antibiotics containing a lactone ring, of which the first and best known is erythromycin.

    Example sentencesExamples
    • Methylation does not affect the function of the adenine residue other than to help the organism become less susceptible to the macrolide class of antibiotics.
    • As with other currently available fluoroquinolone and macrolide antibiotics, QTc interval prolongation has been linked to the use of telithromycin.
    • Trials investigating the role of macrolide antibiotic therapy in patients with acute coronary syndromes are inconclusive.
    • Oral antibiotic therapy with macrolides and cephalosporines for presumed pneumonia was started, with a favorable response after 5 days of therapy.
    • If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.

Origin

1950s: from macro- + l(actone) + -ide.

Definition of macrolide in US English:

macrolide

nounˈmakrəˌlīd
  • Any of a class of antibiotics containing a lactone ring, of which the first and best known is erythromycin.

    Example sentencesExamples
    • Oral antibiotic therapy with macrolides and cephalosporines for presumed pneumonia was started, with a favorable response after 5 days of therapy.
    • Trials investigating the role of macrolide antibiotic therapy in patients with acute coronary syndromes are inconclusive.
    • If antibiotics are required, one that is active against gram-positive organisms such as penicillinase-resistant penicillins, cephalosporins, macrolides, or fluoroquinolones should be chosen.
    • Methylation does not affect the function of the adenine residue other than to help the organism become less susceptible to the macrolide class of antibiotics.
    • As with other currently available fluoroquinolone and macrolide antibiotics, QTc interval prolongation has been linked to the use of telithromycin.

Origin

1950s: from macro- + l(actone) + -ide.

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