Relating to the prescription of a drug for a condition other than that for which it has been officially approved.
用于说明书标明以外的用途的；没被临床试验认可的
the off-label use of potent antipsychotic medications
强效抗精神病药物未按标明用途的使用。
Example sentencesExamples
In British general practice, about a tenth of prescriptions for children are for off-label use of drugs.
Knight Ridder identified more than 800 reports filed during 2002 of serious reactions involving off-label prescriptions for its sample of 45 drugs.
It is a little absurd to blame animal safety data for hazards encountered from off-label prescribing.
Although off-label prescribing is legal, the US Food and Drug Administration prohibits drug companies from promoting such use to doctors.
That these off-label indications were not measured in the approved trials must be made clear, however.
Her doctor had prescribed Prozac off-label for an eating disorder.
Though these uses aren't approved by the FDA, doctors can prescribe thalidomide for other indications, sometimes called off-label uses.
That 40% of doctors prescribe off-label drugs does not surprise me.
Potentially fatal toxicities occur with off-label use of cancer drugs.
A study in Holland found almost one in four prescriptions for children were for drugs that are not licensed for use on children or that are prescribed off-label - outside the terms of the licence.
It states: ‘Hospital trusts in the UK are advising clinicians not to prescribe off-label drugs for palliation, so clinicians find themselves in an untenable position.’
In addition, the off-label use of any medical product comes with associated risks.
What protection do pregnant women have when it comes to the off-label use of obstetrical drugs?
The off-label use of capsaicin cream for treating painful scars is heretofore unreported.
In the United States once a drug is approved doctors who are willing to do so can prescribe it for off-label uses.
In 1993, he was successful in a suit that forced the FDA to relax its rules prohibiting drug companies from promoting off-label prescribing.
The drug's off-label users were mostly bodybuilders.
Current studies have not established safe and optimal dosages for either of these off-label uses.
This issue affects all doctors and off-label drugs will be needed more often for very ill children reflecting the higher usage in hospital.
A physician is free to use a medical device for an off-label purpose, if, in the physician's medical judgment, he or she believes that use of the device will benefit the patient.
Definition of off-label in US English:
off-label
adjective
Relating to the prescription of a drug for a condition other than that for which it has been officially approved.
用于说明书标明以外的用途的；没被临床试验认可的
the off-label use of potent antipsychotic medications
强效抗精神病药物未按标明用途的使用。
as adverbchildren with severe anxiety disorders are given antidepressants off label
Example sentencesExamples
Although off-label prescribing is legal, the US Food and Drug Administration prohibits drug companies from promoting such use to doctors.
What protection do pregnant women have when it comes to the off-label use of obstetrical drugs?
In addition, the off-label use of any medical product comes with associated risks.
Knight Ridder identified more than 800 reports filed during 2002 of serious reactions involving off-label prescriptions for its sample of 45 drugs.
Potentially fatal toxicities occur with off-label use of cancer drugs.
The drug's off-label users were mostly bodybuilders.
This issue affects all doctors and off-label drugs will be needed more often for very ill children reflecting the higher usage in hospital.
Though these uses aren't approved by the FDA, doctors can prescribe thalidomide for other indications, sometimes called off-label uses.
In British general practice, about a tenth of prescriptions for children are for off-label use of drugs.
Current studies have not established safe and optimal dosages for either of these off-label uses.
A study in Holland found almost one in four prescriptions for children were for drugs that are not licensed for use on children or that are prescribed off-label - outside the terms of the licence.
It is a little absurd to blame animal safety data for hazards encountered from off-label prescribing.
Her doctor had prescribed Prozac off-label for an eating disorder.
In 1993, he was successful in a suit that forced the FDA to relax its rules prohibiting drug companies from promoting off-label prescribing.
A physician is free to use a medical device for an off-label purpose, if, in the physician's medical judgment, he or she believes that use of the device will benefit the patient.
In the United States once a drug is approved doctors who are willing to do so can prescribe it for off-label uses.
That these off-label indications were not measured in the approved trials must be made clear, however.
That 40% of doctors prescribe off-label drugs does not surprise me.
The off-label use of capsaicin cream for treating painful scars is heretofore unreported.
It states: ‘Hospital trusts in the UK are advising clinicians not to prescribe off-label drugs for palliation, so clinicians find themselves in an untenable position.’