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词汇 oligomerize
释义

Definition of oligomerize in English:

oligomerize

(also oligomerise)
verb əˈlɪɡəmərʌɪz
[with object]Chemistry
  • Join a number of molecules of (a monomer) together to form an oligomer.

    〔化〕低聚

    Example sentencesExamples
    • We were interested in exploring this possibility, to confirm whether LPPs can oligomerise, and if they do, whether oligomerisation is required for either in vitro or in vivo activity.
    • These results indicate that BD-M13 coat protein in the studied DOPC-containing bilayers does not oligomerize.
    • Two possibilities are that peptide inserts as a monomer and transposes its environment to initiate aggregation into oligomers/protofibrils or that the peptide oligomerizes and then inserts into membranes to stabilize itself.
    • Our control experiment indicated that all membrane-associated lysenin was oligomerized under the experimental conditions.
    • The monomers oligomerize after insertion into the bilayer.
    • ABSTRACT We have used an in vitro system that mimics the assembly of immature Moloney murine leukemia virus (M-MuLV) particles to examine how viral structural proteins oligomerize at membrane interfaces.
    • The melting of unlabeled Mg-G-actin could not be measured reliably because of its tendency to oligomerize at concentrations much lower than those used in the DSC.
    • Though the conditions are far from those present when a connexin molecule oligomerizes into a functional gap junction in a mammalian cell, Cx43CT oligomerization did not exceed that which occurs in a connexon.
    • In addition, the high propensity of lead to oligomerize syt II offers a possible molecular explanation for how lead interferes with calcium-evoked neurotransmitter release.
    • First, the tetrameric structure of the protein and the propensity of tetramers to oligomerize further into aggregates impeded its utility as a fusion partner.
    • Following that nucleation step, silencing spreads along the chromosome, as observed or proposed for related systems and as supported by the fact that Swi6 can oligomerize and cover large chromosomal regions.
    • Catalytic composition and process for oligomerising ethylene in particular to 1-butene and/or 1-hexene
    • In this case the channels are largely composed of naturally occurring Lys and Ser residues that form alpha helices and are engineered to oligomerize through specific residue interactions.
    • We conclude that VPU-TM tends to oligomerize as a pentamer under the present simulation conditions, which we postulate are representative of the accessible states of the protein.
    • It will be interesting to verify whether CBD sites have the same critical role in proteins that do not oligomerize, when their representation in public databases will be sufficient to allow an analysis similar to that presented here.
    • Taken together, these data suggest that in solution PLC-Gγ dimers further oligomerize to a higher order species such as tetramers.
    • However, the binding of CypA to oligomerized His 6 CA allows for this change.
    • When they are oligomerized by a gold particle or by liganding, they have a much lower chance of crossing a picket line, due to the increased interactions with the anchored membrane-protein pickets.
    • Both syt I and syt II studied in our laboratory have glycine at this position, yet only syt II was observed to oligomerize.
    • Ply-tnb retained the ability to bind to the phospholipid membrane but lacked the ability to oligomerize, confirming that the processes of cell binding and oligomerization are functionally separate.

Derivatives

  • oligomerization

  • noun
    Chemistry
    • Compatible solutes like PEG - 6000 promote the oligomerization of PEPC, increase the enzyme activity and decrease its malate sensitivity.
      Example sentencesExamples
      • Such enhanced confinement and binding effects induced by oligomerization or molecular complex formation are collectively termed oligomerization-induced trapping.
      • The membrane-associated [beta] strand structure is oligomeric, and this oligomerization can result from association of soluble peptide monomers with membranes.
      • His studies, in collaboration with BP Amoco Chemicals and Unilever, include oligomerisation, polymerisation, alkylation and acylation in ionic liquids.
      • The solvent serves as a reaction, polymerization or oligomerization diluent.
      • This modest affinity might be linked to a significant loss of configurational entropy upon oligomerization, which would be the case if folding and assembly processes are coupled.
      • Explicitly, no oligomerization or dimer dissociation appears to be likely, attributing changes in the binding constant to the immediate microenvironment of the binding sites.
      • The structure of these aggregates appears not to be amorphous and seems to be formed by oligomerization of prolactin molecules involving specific sites.
      • Therefore, it was concluded that the use of butanol instead of chloroform/methanol may decrease the oligomerization of SP-B.
      • As already discussed, increases in ionic strength seem to enhance the hydrophobicity of the peptide, which can be stabilized by peptide insertion into the lipid film and/or lipid oligomerization.
      • Second, the C-propeptides of vertebrate procollagen also contain variable sequences, which promote selective oligomerization of structurally compatible monomers.
      • Soluble peptide oligomerization is considered within the context of previous studies from our and other research groups.
      • The B subunit carries a C-terminal extension responsible for the oligomerization of higher plant chloroplast GAPDH into an A 8 B 8 regulatory form.
      • I - 3 - C is an unstable molecule, and undergoes oligomerization in the gut to a number of different compounds, including diindolylmethane.
      • This is the first time that a LPP has been shown to dimerise, although protein oligomerisation per se is not novel.
      • Such an implied cooperative enhancement of complex aggregation is in support of the notion of lipid complex oligomerization.
      • The only Copepoda protein analyzed for oligomerization is also a monomer.
      • Studies of peptide aqueous oligomerization can address this question.
      • Another domain is usually responsible for dimerization or oligomerization of the transcription factor monomers.
      • The FRET measurements also show a slow increase in oligomerization of EGFR monomers after growth factor binding.
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