Definition of oligonucleotide in English:

oligonucleotide

noun ˌɒlɪɡə(ʊ)ˈnjuːklɪətʌɪdˌäləɡōˈn(y)o͞oklēətīd

Biochemistry

A polynucleotide whose molecules contain a relatively small number of nucleotides.
〔生化〕低（聚）核苷酸，寡核苷酸
Example sentencesExamples
- Creation and purification of the double-labeled oligonucleotide is synthetically demanding.
- The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis.
- Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically.
- Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines.
- The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide.
- On single-stranded oligonucleotides, all the guanines are oxidized to the same extent.
- In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus.
- This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2.
- The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides.
- The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides.
- This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified.
- We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.
- The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane.
- The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing.
- For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs.
- One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell.
- In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences.
- Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve.
- These studies demonstrate that pre-existing cytosine methylation on oligonucleotides…
- The latter is generally restricted to oligonucleotides but offers higher specificity.

Definition of oligonucleotide in US English:

oligonucleotide

nounˌäləɡōˈn(y)o͞oklēətīd

Biochemistry

A polynucleotide whose molecules contain a relatively small number of nucleotides.
〔生化〕低（聚）核苷酸，寡核苷酸
Example sentencesExamples
- In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus.
- For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs.
- This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2.
- On single-stranded oligonucleotides, all the guanines are oxidized to the same extent.
- The latter is generally restricted to oligonucleotides but offers higher specificity.
- Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve.
- This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified.
- We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes.
- The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis.
- Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically.
- The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing.
- One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell.
- The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides.
- The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide.
- The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane.
- Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines.
- Creation and purification of the double-labeled oligonucleotide is synthetically demanding.
- The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides.
- In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences.
- These studies demonstrate that pre-existing cytosine methylation on oligonucleotides…

词汇	oligonucleotide
释义	Definition of oligonucleotide in English: oligonucleotide noun ˌɒlɪɡə(ʊ)ˈnjuːklɪətʌɪdˌäləɡōˈn(y)o͞oklēətīd Biochemistry A polynucleotide whose molecules contain a relatively small number of nucleotides. 〔生化〕低（聚）核苷酸，寡核苷酸 Example sentencesExamples Creation and purification of the double-labeled oligonucleotide is synthetically demanding. The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis. Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically. Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines. The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide. On single-stranded oligonucleotides, all the guanines are oxidized to the same extent. In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus. This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2. The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides. The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides. This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified. We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes. The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane. The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing. For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs. One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell. In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences. Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve. These studies demonstrate that pre-existing cytosine methylation on oligonucleotides… The latter is generally restricted to oligonucleotides but offers higher specificity. Definition of oligonucleotide in US English: oligonucleotide nounˌäləɡōˈn(y)o͞oklēətīd Biochemistry A polynucleotide whose molecules contain a relatively small number of nucleotides. 〔生化〕低（聚）核苷酸，寡核苷酸 Example sentencesExamples In apoptosis, DNA is degraded into oligonucleotides with a few hundreds of basepairs that subsequently diffuse out of the nucleus. For single bulges in RNA oligonucleotides, the conformation usually depends on the nature of the flanking base pairs. This was followed minutes later by the injection of the oligonucleotide complementary to the DNA strand immobilized on sphere S2. On single-stranded oligonucleotides, all the guanines are oxidized to the same extent. The latter is generally restricted to oligonucleotides but offers higher specificity. Liposomal formulations of genetic drugs such as antisense oligonucleotides and plasmid DNA are difficult to achieve. This problem would be enhanced using arrays composed of long oligonucleotides since only RNAs whose protected regions overlap with the oligo sequence would be identified. We have been examining the potential use of oligonucleotides to direct nucleotide exchanges in episomal and chromosomal genes. The purity of the double-stranded oligonucleotides was confirmed by polyacrylamide gel electrophoresis. Probes are typically fairly short sequences of DNA nucleotides, called oligonucleotides, made synthetically. The proper orientation and the sequence of the cloned oligonucleotides were checked by nucleotide sequencing. One important application is gene therapy, where it is necessary to deliver a gene or a synthetic oligonucleotide into the cell. The unmodified polynucleotides may be DNA, RNA or synthesized oligonucleotides. The latter is conjugated to primer oligonucleotides that are pre-annealed to a complementary circular oligonucleotide. The peptides can be linked to a large protein or an oligonucleotide, which may then be carried through the cell membrane. Intermolecular tetrameric complexes are usually only formed by short oligonucleotides that contain single tracts of contiguous guanines. Creation and purification of the double-labeled oligonucleotide is synthetically demanding. The unzipping direction (order of nucleotides unzipped) was controlled by the selection of oligonucleotides. In vitro studies on novel DNA structures have mainly involved synthetic oligonucleotides based on naturally occurring sequences. These studies demonstrate that pre-existing cytosine methylation on oligonucleotides…
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