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词汇 replicon
释义

Definition of replicon in English:

replicon

noun ˈrɛplɪkɒnˈrepləkän
Biology
  • A nucleic acid molecule, or part of one, which replicates as a unit, beginning at a specific site within it.

    〔生〕复制子

    Example sentencesExamples
    • This defective recovery of DNA replication suggests an inability to coordinate lesion bypass or to initiate new replicons.
    • This small-scale patterning might result from different mutational biases on the leading and lagging strands, but only if replicon size in germ line cells were restricted to a few kilobases.
    • An important category of small replicons are the prophages, phages and other virus types.
    • Nuclei have numerous replicons origins per chromosome, which can be replicated simultaneously - so replication time is mechanistically independent of genome size and can be far less than in bacteria.
    • A characteristic feature of the cellular response to ionizing radiation exposure is inhibition of replicon initiation.

Origin

1960s: from replication + -on.

Definition of replicon in US English:

replicon

nounˈrepləkän
Biology
  • A nucleic acid molecule, or part of one, which replicates as a unit, beginning at a specific site within it.

    〔生〕复制子

    Example sentencesExamples
    • This defective recovery of DNA replication suggests an inability to coordinate lesion bypass or to initiate new replicons.
    • A characteristic feature of the cellular response to ionizing radiation exposure is inhibition of replicon initiation.
    • Nuclei have numerous replicons origins per chromosome, which can be replicated simultaneously - so replication time is mechanistically independent of genome size and can be far less than in bacteria.
    • An important category of small replicons are the prophages, phages and other virus types.
    • This small-scale patterning might result from different mutational biases on the leading and lagging strands, but only if replicon size in germ line cells were restricted to a few kilobases.

Origin

1960s: from replication + -on.

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