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词汇 spironolactone
释义

Definition of spironolactone in English:

spironolactone

noun ˌspʌɪrənə(ʊ)ˈlaktəʊnˌspīrənōˈlaktōn
mass nounMedicine
  • A steroid drug which promotes sodium excretion and is used in the treatment of certain types of oedema and hypertension.

    〔医〕安体舒通,螺内酯

    Example sentencesExamples
    • About two years before this admission he had developed ascites, and treatment with salt restriction, spironolactone, and frusemide was started.
    • For example, ACE inhibitors, beta-blockers, ARBs, spironolactone and digoxin are probably not necessary in all patients.
    • Recent research has shown that treatment with spironolactone improves mortality and hospital readmission rates.
    • Pharmacologic agents used have included hydrochlorothiazide, spironolactone, furosemide, propranolol, or hydralazine.
    • We restricted our analyses to loop diuretics, angiotensin converting enzyme inhibitors, blockers, spironolactone, and digoxin.

Origin

1960s: from spiro-1 (sense 2) + lactone, with the insertion of -one.

Definition of spironolactone in US English:

spironolactone

nounˌspīrənōˈlaktōn
Medicine
  • A steroid derivative that is an aldosterone antagonist, which promotes sodium excretion and is used in the treatment of certain types of edema and hypertension.

    〔医〕安体舒通,螺内酯

    Chemical formula: C₂₄H₃₂O₄S

    Example sentencesExamples
    • Pharmacologic agents used have included hydrochlorothiazide, spironolactone, furosemide, propranolol, or hydralazine.
    • Recent research has shown that treatment with spironolactone improves mortality and hospital readmission rates.
    • About two years before this admission he had developed ascites, and treatment with salt restriction, spironolactone, and frusemide was started.
    • For example, ACE inhibitors, beta-blockers, ARBs, spironolactone and digoxin are probably not necessary in all patients.
    • We restricted our analyses to loop diuretics, angiotensin converting enzyme inhibitors, blockers, spironolactone, and digoxin.

Origin

1960s: from spiro- (sense 2) + lactone, with the insertion of -one.

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