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词汇 von Willebrand's disease
释义

Definition of von Willebrand's disease in English:

von Willebrand's disease

nounˈwɪləbrandvän ˈviləbränts dəˌzēz
mass nounMedicine
  • An inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).

    〔医〕冯·维勒布兰德氏病

    Example sentencesExamples
    • The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.
    • Bloat, epilepsy and heart related problems are also reported, as are von Willebrand's disease and hemophilia A.
    • There is also impairment of the platelet response to thrombin, collagen, fibrinogen, and von Willebrand factor.
    • Patients with Type 3 (and some with Type 2A and 2B) will need treatment with humate p, a medication derived from human plasma that contains both factor VIII and von Willebrand factor.
    • In most patients with von Willebrand disease, factor VIII activity and plasma levels of von Willebrand factor are decreased.

Origin

1940s: named after Erik A. von Willebrand (1870–1949), Finnish physician.

Definition of von Willebrand's disease in US English:

von Willebrand's disease

nounvän ˈviləbränts dəˌzēz
Medicine
  • An inherited disorder characterized by a tendency to bleed, caused by deficiency or abnormality of a plasma coagulation factor (von Willebrand factor).

    〔医〕冯·维勒布兰德氏病

    Example sentencesExamples
    • Patients with Type 3 (and some with Type 2A and 2B) will need treatment with humate p, a medication derived from human plasma that contains both factor VIII and von Willebrand factor.
    • The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.
    • In most patients with von Willebrand disease, factor VIII activity and plasma levels of von Willebrand factor are decreased.
    • Bloat, epilepsy and heart related problems are also reported, as are von Willebrand's disease and hemophilia A.
    • There is also impairment of the platelet response to thrombin, collagen, fibrinogen, and von Willebrand factor.

Origin

1940s: named after Erik A. von Willebrand (1870–1949), Finnish physician.

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