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词汇 sulphasalazine
释义

Definition of sulphasalazine in English:

sulphasalazine

(also sulfasalazine)
nounˌsʌlfəˈsaləziːn
mass nounMedicine
  • A sulphonamide antibiotic used to treat ulcerative colitis and Crohn's disease.

    〔医〕柳氮磺嘧啶

    Example sentencesExamples
    • Supplementation with folic acid (15 mg/day for one month) prevents folate deficiency in patients with inflammatory bowel disease treated with sulfasalazine.
    • This failed to respond to sulfasalazine or doxycycline, and was not controlled with nonsteroidal agents; eventually, a small dose of prednisone was required on a long-term basis.
    • At six and 12 months, there was no difference in ACR20 response rate between patients treated with leflunomide and patients treated with sulfasalazine or methotrexate.
    • All of the women included in the case part of the study were taking at least one of the following folic acid antagonists: trimethoprim, triamterene, sulfasalazine, phenytoin, phenobarbital, primidone and carbamazepine.
    • Almost all sulfonamides are anti-infectives: however, sulfasalazine which is used to treat ulcerative colitis and Crohn's disease, is also included.

Origin

1960s: from sulpha- + sal(icylic acid) + azine.

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