Definition of sulphasalazine in English:

sulphasalazine

(also sulfasalazine)

nounˌsʌlfəˈsaləziːn

mass nounMedicine

A sulphonamide antibiotic used to treat ulcerative colitis and Crohn's disease.
〔医〕柳氮磺嘧啶
Example sentencesExamples
- Supplementation with folic acid (15 mg/day for one month) prevents folate deficiency in patients with inflammatory bowel disease treated with sulfasalazine.
- This failed to respond to sulfasalazine or doxycycline, and was not controlled with nonsteroidal agents; eventually, a small dose of prednisone was required on a long-term basis.
- At six and 12 months, there was no difference in ACR20 response rate between patients treated with leflunomide and patients treated with sulfasalazine or methotrexate.
- All of the women included in the case part of the study were taking at least one of the following folic acid antagonists: trimethoprim, triamterene, sulfasalazine, phenytoin, phenobarbital, primidone and carbamazepine.
- Almost all sulfonamides are anti-infectives: however, sulfasalazine which is used to treat ulcerative colitis and Crohn's disease, is also included.

Origin

1960s: from sulpha- + sal(icylic acid) + azine.

词汇	sulphasalazine
释义	Definition of sulphasalazine in English: sulphasalazine (also sulfasalazine) nounˌsʌlfəˈsaləziːn mass nounMedicine A sulphonamide antibiotic used to treat ulcerative colitis and Crohn's disease. 〔医〕柳氮磺嘧啶 Example sentencesExamples Supplementation with folic acid (15 mg/day for one month) prevents folate deficiency in patients with inflammatory bowel disease treated with sulfasalazine. This failed to respond to sulfasalazine or doxycycline, and was not controlled with nonsteroidal agents; eventually, a small dose of prednisone was required on a long-term basis. At six and 12 months, there was no difference in ACR20 response rate between patients treated with leflunomide and patients treated with sulfasalazine or methotrexate. All of the women included in the case part of the study were taking at least one of the following folic acid antagonists: trimethoprim, triamterene, sulfasalazine, phenytoin, phenobarbital, primidone and carbamazepine. Almost all sulfonamides are anti-infectives: however, sulfasalazine which is used to treat ulcerative colitis and Crohn's disease, is also included. Origin 1960s: from sulpha- + sal(icylic acid) + azine.
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