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词汇 tolbutamide
释义

Definition of tolbutamide in English:

tolbutamide

noun tɒlˈbjuːtəmʌɪdtälˈbyo͞odəˌmīd
mass nounMedicine
  • A synthetic compound used to lower blood sugar levels in the treatment of diabetes.

    〔医〕甲苯磺丁脲,甲糖宁

    Alternative name: 1-butyl-3-tosylurea; chemical formula: C₁₂H₁₈N₂O₃S

    Example sentencesExamples
    • Alcohol-extracted charantin from Momordica charantia consists of mixed steroids and was found to be more potent than the oral hypoglycemic agent tolbutamide in an animal study.
    • Examples of sulfonylureas include tolbutamide, chlorpropamide, glyburide and glipizide.
    • In some studies, karela extract has shown more hypoglycemic effects than the drug tolbutamide.
    • Based on studies of the distribution of first-generation sulfonylureas into breast milk, the AAP considers tolbutamide to be compatible with breast-feeding.
    • For example, sulfonamides used for infection were noted to lower blood sugar and led to drugs such as tolbutamide for diabetes.

Origin

1950s: from tol(uene) + but(yl) + amide.

Definition of tolbutamide in US English:

tolbutamide

nountälˈbyo͞odəˌmīd
Medicine
  • A synthetic compound used to lower blood sugar levels in the treatment of diabetes.

    〔医〕甲苯磺丁脲,甲糖宁

    Alternative name: 1-butyl-3-tosylurea; chemical formula: C₁₂H₁₈N₂O₃S

    Example sentencesExamples
    • Examples of sulfonylureas include tolbutamide, chlorpropamide, glyburide and glipizide.
    • For example, sulfonamides used for infection were noted to lower blood sugar and led to drugs such as tolbutamide for diabetes.
    • Based on studies of the distribution of first-generation sulfonylureas into breast milk, the AAP considers tolbutamide to be compatible with breast-feeding.
    • In some studies, karela extract has shown more hypoglycemic effects than the drug tolbutamide.
    • Alcohol-extracted charantin from Momordica charantia consists of mixed steroids and was found to be more potent than the oral hypoglycemic agent tolbutamide in an animal study.

Origin

1950s: from tol(uene) + but(yl) + amide.

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