| 释义 |
Definition of torsade de pointes in English: torsade de pointesnoun tɔːˌsɑːd də ˈpwãttôrˌsäd də ˈpwänt mass nounMedicine A form of tachycardia in which the electrical pulse in the heart undergoes a cyclical variation in strength, giving a characteristic electrocardiogram resembling a twisted fringe of spikes. 〔医〕尖端扭转型室性心动过速 Example sentencesExamples - In addition, blockers of PKA and CaMKII have been shown to eliminate EADs and torsade de pointes in ventricular myocytes isolated from rabbits.
- Many antipsychotic drugs can prolong the QT interval, and many have been linked to cases of torsade de pointes.
- Unlike methadone, LAAM was found in post-marketing treatment to be associated with prolonged QTc interval and torsade de pointes, thus relegating this therapy as second-line opiate replacement therapy.
- Spontaneous torsade de pointes was suppressed, and the vulnerable window during which TdP-induction occurs was also reduced in both models.
- These changes may result in cardiac arrhythmias, such as torsade de pointes, atrial fibrillation, supraventricular tachycardia, and ventricular tachycardia.
- Patients who experience dizziness, palpitations, or syncope while taking ziprasidone therapy should be evaluated further for the potential occurrence of torsade de pointes.
- Certain psychotropic medications and somatic medications can increase the risk of lethal torsade de pointes through a mechanism of blocking cardiac conduction channels.
- In one case, the mutation led to acquired (drug-induced) torsade de pointes and ventricular fibrillation.
- Such prolongation increases the risk of torsade de pointes, a ventricular tachycardia-fibrillation with a characteristic electrocardiogram presentation.
- Although class III antiarrhythmic agents can suppress ventricular arrhythmias, they are also associated with torsade de pointes.
- IV magnesium sulfate can be used to control torsade de pointes or a prolonged QT interval: 2 g of magnesium sulfate IV over 5 to 10 minutes depending on acuity.
Origin1960s: French, literally 'twist of spikes'. Definition of torsade de pointes in US English: torsade de pointesnountôrˌsäd də ˈpwänt Medicine A form of tachycardia in which the electrical pulse in the heart undergoes a cyclical variation in strength, giving a characteristic electrocardiogram resembling a twisted fringe of spikes. 〔医〕尖端扭转型室性心动过速 Example sentencesExamples - Although class III antiarrhythmic agents can suppress ventricular arrhythmias, they are also associated with torsade de pointes.
- IV magnesium sulfate can be used to control torsade de pointes or a prolonged QT interval: 2 g of magnesium sulfate IV over 5 to 10 minutes depending on acuity.
- In one case, the mutation led to acquired (drug-induced) torsade de pointes and ventricular fibrillation.
- Certain psychotropic medications and somatic medications can increase the risk of lethal torsade de pointes through a mechanism of blocking cardiac conduction channels.
- Such prolongation increases the risk of torsade de pointes, a ventricular tachycardia-fibrillation with a characteristic electrocardiogram presentation.
- These changes may result in cardiac arrhythmias, such as torsade de pointes, atrial fibrillation, supraventricular tachycardia, and ventricular tachycardia.
- Unlike methadone, LAAM was found in post-marketing treatment to be associated with prolonged QTc interval and torsade de pointes, thus relegating this therapy as second-line opiate replacement therapy.
- Patients who experience dizziness, palpitations, or syncope while taking ziprasidone therapy should be evaluated further for the potential occurrence of torsade de pointes.
- Spontaneous torsade de pointes was suppressed, and the vulnerable window during which TdP-induction occurs was also reduced in both models.
- Many antipsychotic drugs can prolong the QT interval, and many have been linked to cases of torsade de pointes.
- In addition, blockers of PKA and CaMKII have been shown to eliminate EADs and torsade de pointes in ventricular myocytes isolated from rabbits.
Origin1960s: French, literally ‘twist of spikes’. |