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词汇 tachyphylaxis
释义

Definition of tachyphylaxis in English:

tachyphylaxis

nounˌtakɪfɪˈlaksɪsˌtakəfiˈlaksəs
mass nounMedicine
  • Rapidly diminishing response to successive doses of a drug, rendering it less effective. The effect is common with drugs acting on the nervous system.

    〔医〕(因连续服用同一种药物而产生的)快速抗药反应;快速减敏

    Example sentencesExamples
    • Topical steroids should be applied no more than twice a day; more frequent use provides no advantage and may induce tachyphylaxis.
    • Trebling doses of histamine diphosphate were chosen instead of the usual doubling dose because of the half-life of lidocaine, the number of challenges, and the need to minimize possible tachyphylaxis of the histamine effect.
    • Giving methotrexate concurrently, however, suppressed tachyphylaxis, probably by preventing the production of human antichimeric antibodies.
    • The efficacy of calcipotriene is comparable to mid-potency topical corticosteroids; however, it does not cause skin atrophy or tachyphylaxis.
    • This spirometric improvement was maintained throughout the 13-week period without any evidence of tachyphylaxis.

Definition of tachyphylaxis in US English:

tachyphylaxis

nounˌtakəfiˈlaksəs
Medicine
  • Rapidly diminishing response to successive doses of a drug, rendering it less effective. The effect is common with drugs acting on the nervous system.

    〔医〕(因连续服用同一种药物而产生的)快速抗药反应;快速减敏

    Example sentencesExamples
    • This spirometric improvement was maintained throughout the 13-week period without any evidence of tachyphylaxis.
    • Topical steroids should be applied no more than twice a day; more frequent use provides no advantage and may induce tachyphylaxis.
    • The efficacy of calcipotriene is comparable to mid-potency topical corticosteroids; however, it does not cause skin atrophy or tachyphylaxis.
    • Giving methotrexate concurrently, however, suppressed tachyphylaxis, probably by preventing the production of human antichimeric antibodies.
    • Trebling doses of histamine diphosphate were chosen instead of the usual doubling dose because of the half-life of lidocaine, the number of challenges, and the need to minimize possible tachyphylaxis of the histamine effect.
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