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词汇 telomere
释义

Definition of telomere in English:

telomere

nounˈtiːlə(ʊ)mɪəˈtɛlə(ʊ)mɪəˈtelə-
Genetics
  • A compound structure at the end of a chromosome.

    〔遗传〕(染色体)端粒

    Example sentencesExamples
    • It has long been thought that the grouping of telomeres is important for chromosome pairing and subsequent synapsis.
    • These two genes are tightly linked to the left telomere of the X chromosome.
    • In normal somatic cells, the telomeres shorten with replicative age, and telomerase is not detected.
    • Which chromosomes have the shortest telomeres depends only on telomere length in the original parent mice.
    • Without telomeres, the chromosomes would ‘fray’ when the cells divided.

Derivatives

  • telomeric

  • adjective
    Genetics
    • This ancestral telomeric element has evolved to optimize telomere maintenance.
      Example sentencesExamples
      • To assess telomeric localization, we quantitated the number of telomeric foci in the various strain backgrounds.
      • Such a widespread conservation of telomeric silencing among eukaryotes suggests that it is fundamental to telomere function.
      • In both normal-length and elongated telomeres, telomeric turnover was found to involve all but the innermost few repeats.
      • Based on these findings, it is reasonable to conclude that telomeric regions of mitotic chromosomes are not unusually susceptible to crossover.

Origin

1940s: from Greek telos 'end' + meros 'part'.

Definition of telomere in US English:

telomere

nounˈtelə-
Genetics
  • A compound structure at the end of a chromosome.

    〔遗传〕(染色体)端粒

    Example sentencesExamples
    • These two genes are tightly linked to the left telomere of the X chromosome.
    • It has long been thought that the grouping of telomeres is important for chromosome pairing and subsequent synapsis.
    • In normal somatic cells, the telomeres shorten with replicative age, and telomerase is not detected.
    • Which chromosomes have the shortest telomeres depends only on telomere length in the original parent mice.
    • Without telomeres, the chromosomes would ‘fray’ when the cells divided.

Origin

1940s: from Greek telos ‘end’ + meros ‘part’.

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