On the scalp of patients who are predisposed to the condition, androgens lead to miniaturisation, a switch from terminal to vellus or vellus-like follicles, and a reduction in the duration of anagen.
A 0.1% melatonin or a placebo solution was applied on the scalp once daily for 6 months and trichograms were performed to assess anagen and telogen hair rate.
Alteration of matrix cell activity during anagen, by whatever method chosen, increases the amount of time from removal to regrowth.
Elsewhere, cysts containing central keratinous material were associated with a peripheral basaloid epithelial proliferation showing the formation of buds mimicking abortive anagen hair follicles.
Telogen effluvium is diffuse hair loss caused by any condition or situation that shifts the normal distribution of follicles in anagen to a telogen-predominant distribution.