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词汇 aneuploid
释义

Definition of aneuploid in English:

aneuploid

adjectiveˈanjʊplɔɪdˈanyo͝oˌploid
Genetics
  • Having an abnormal number of chromosomes in a haploid set.

    Example sentencesExamples
    • When colonies are formed, the resulting cells tend to have euploid genomes derived from the aneuploid state by chromosome loss.
    • All women are also offered an ultrasound scan for anomalies at 19 weeks' gestation, and invasive testing is offered in selected cases where structural anomalies are seen that suggest the fetus is aneuploid.
    • Fig 5 shows euploid and aneuploid colonies formed after the shift-down experiment.
    • The percentages of aneuploid bone marrow leukocytes were higher than those of aneuploid sperm for the two upper THH dose groups and for the positive control group.
    • Ten of 18 diploid neoplasms were associated with an adverse event, and 2 of 9 aneuploid neoplasms were associated with an adverse event.
    • Ploidy analysis shows that the keratinocytes in the large cell acanthoma are frequently aneuploid.
    • First, of the population of tetraploid cells that enter stationary phase, both euploid and aneuploid members can be rescued by starvation in water.
    • Almost 50% of spontaneous abortions are aneuploid or polyploid and the incidence of numerical aberrations in live-born young is ~ 5/1000 births.
    • Patients with aneuploid tumors have a poorer five-year survival rate than patients with diploid tumors.
    • DNA ploidy analysis on Feulgenstained sections indicated that the large cell region was composed of predominantly tetraploid and aneuploid cells.

Derivatives

  • aneuploidy

    〔遗传〕非整倍体的

  • nounˈanjʊplɔɪdiˈænjəˌploɪdi
    mass nounGenetics
    • The condition of having an abnormal number of chromosomes in a haploid set.

      a method for detecting aneuploidy in dividing cells
      Example sentencesExamples
      • The most direct way to assess chromosomal aneuploidy is to evaluate chromosome numbers in metaphase cells.
      • Special schemes were not required to avoid aneuploidy of X chromosome segments because exchange occurred in heterochromatin.
      • It remains to be determined whether individual genes that contribute to MR in cases of aneuploidy or other chromosomal defects can mutate to an MR phenotype individually.

Definition of aneuploid in US English:

aneuploid

adjectiveˈanyo͝oˌploid
Genetics
  • Having an abnormal number of chromosomes in a haploid set.

    Example sentencesExamples
    • The percentages of aneuploid bone marrow leukocytes were higher than those of aneuploid sperm for the two upper THH dose groups and for the positive control group.
    • Ploidy analysis shows that the keratinocytes in the large cell acanthoma are frequently aneuploid.
    • First, of the population of tetraploid cells that enter stationary phase, both euploid and aneuploid members can be rescued by starvation in water.
    • Patients with aneuploid tumors have a poorer five-year survival rate than patients with diploid tumors.
    • Fig 5 shows euploid and aneuploid colonies formed after the shift-down experiment.
    • Ten of 18 diploid neoplasms were associated with an adverse event, and 2 of 9 aneuploid neoplasms were associated with an adverse event.
    • When colonies are formed, the resulting cells tend to have euploid genomes derived from the aneuploid state by chromosome loss.
    • Almost 50% of spontaneous abortions are aneuploid or polyploid and the incidence of numerical aberrations in live-born young is ~ 5/1000 births.
    • All women are also offered an ultrasound scan for anomalies at 19 weeks' gestation, and invasive testing is offered in selected cases where structural anomalies are seen that suggest the fetus is aneuploid.
    • DNA ploidy analysis on Feulgenstained sections indicated that the large cell region was composed of predominantly tetraploid and aneuploid cells.
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