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词汇 anticholinergic
释义

Definition of anticholinergic in English:

anticholinergic

adjectiveˌantɪˌkəʊlɪˈnəːdʒɪkˌantī-
Medicine
  • (chiefly of a drug) inhibiting the physiological action of acetylcholine, especially as a neurotransmitter.

    (多指药物)抗胆碱能的

    Example sentencesExamples
    • Thyrotoxicosis, anticholinergic drug poisoning, and amphetamine or cocaine use can result in signs of increased sympathetic activity and altered mental status.
    • Nonetheless, the available anticholinergic drugs (atropine and ipratropium bromide) have limited effects, perhaps because of their nonselectivity.
    • This agent crosses the blood-brain barrier and thereby reverses both central and peripheral effects of the abused anticholinergic drug.
    • They dismiss conventional medical treatment with anticholinergic drugs as inconvenient, unpleasant, and temporary, and they say that patients usually stop using anticholinergic drugs because of a dry mouth.
    • Until further research in primary care settings is performed, there is little evidence to guide family physicians in the choice of anticholinergic medications for urge incontinence.
    • Pharmacologic treatment of overactive bladder symptoms is based on the use of anticholinergic drugs that block the parasympathetic pathways and reduce detrusor muscle contraction.
    • Main outcome measures: Numbers of elderly people with new prescriptions of highly anticholinergic antidepressants and less anticholinergic antidepressants.
    • He thought for a minute and added, ‘So, if we improve cognition by increasing acetylcholine, it makes sense that anticholinergic drugs can make dementia a lot worse.’
    • Amantadine, anticholinergic drugs, selegiline, and non-pharmacological treatments (such as physical therapy) provide symptomatic relief in mildly affected patients.
    • Antihistamine and anticholinergic drugs are relatively inexpensive.
    • The administration of antihypertensive and anticholinergic medications also impairs salivary functions and promotes xerostomia.
    • This study demonstrates that moderate to severe dry mouth is common in patients treated with anticholinergic drugs.
    • Dry mouth is the most common complaint with the oral anticholinergic drugs oxybutynin and tolterodine.
    • Examples of anticholinergic drugs include atropine and ipratropium (Atrovent).
    • In each of these cases, once the iatrogenic etiology of this syndrome was recognized, the patients' symptoms improved rapidly and dramatically with administration of anticholinergic medication.
    • Although statistically significant, the differences between anticholinergic drugs and placebo were small, apart from the increased rate of dry mouth in patients receiving active treatment.
    • Older men with prostatic hypertrophy may benefit from alpha-blocker medications and should be watched for urinary retention if anticholinergic drugs are employed.
    • Use of the anticholinergic drug atropine during tap-water iontophoresis sometimes is helpful, but extreme caution is necessary to avoid toxicity from atropine overdose.
    • Medical management consists of maintenance therapy with anticholinergic inhibitors such as pyridostigmine to relieve symptoms and steroids to treat the autoimmunity.
    • If these measures are not successful, an anticholinergic drug may control the pain.
nounˌantɪˌkəʊlɪˈnəːdʒɪkˌantī-
Medicine
  • An anticholinergic drug.

    抗胆碱能药

    Example sentencesExamples
    • Anticholinergics have been used in an attempt to decrease gastric secretions and increase pH. As with the use of nasogastric tubes, anticholinergics do not decrease hospital stay or pain.
    • Because even small amounts can be fatal, anticholinergics constitute the most dangerous class of abused drugs.
    • Agreement among guidelines is much greater regarding treatment - currently supporting the use of inhaled anticholinergics and antibiotics for initial treatment.
    • Medications that may worsen confusion include anticholinergics, analgesics, cimetidine, central nervous system depressants, lidocaine, and other medications.
    • Both antihistamines and anticholinergics can have anticholinergic side effects, including dry mouth, urinary retention, blurred vision, and exacerbation of narrow-angle glaucoma.
    • New medications, particularly anticholinergics and psychotropic medicines, should be the first suspects if there is a change in a patient's mental status.
    • The medications most often used to help children with neurogenic bladder are called anticholinergics.
    • Acute care of an asthma exacerbation involves the use of inhaled [beta.sub.2] agonists delivered by a metered-dose inhaler with a spacer, or a nebulizer, supplemented by anticholinergics in more severe exacerbations.
    • Moreover, anticholinergics do not appear to be effective for patients whose initial response to beta-agonists is impaired, and at this point, there is no clear consensus regarding their use.
    • They recommend anticholinergics and antihistamines for the treatment of nausea associated with vertigo or motion sickness.
    • Dry mouth, which can be brought on by neuroleptics, antidepressants, and anticholinergics, may worsen the problem.
    • Despite these uncertainties, anticholinergics are increasingly being used in both primary care and secondary care for the treatment of overactive bladder, and this has considerable implications for resources.
    • These drugs are called anticholinergics and include oxybutynin, tolterodine, trospium chloride, and propiverine.
    • Short-term use of anticholinergics or antidiarrheal agents may be effective in combating incontinence associated with diarrhea.
    • Thus, in 1914, anticholinergics by injection or inhalation were considered as first-line asthma therapies.
    • Concomitant use of anticholinergics and beta 2 agonists may be beneficial to the older patient
    • Probably the most common medications used for the treatment of incontinence fall into the general category of anticholinergics or drugs designed to ‘relax’ the bladder.
    • Returning to our clinical scenario, we would recommend that our five-year-old patient with a moderate asthma exacerbation receive anticholinergics in addition to the [beta.sub.2] agonists and oral steroid therapy.
    • However, the effect of chronic treatment with anticholinergics on airway remodeling, responsiveness, and changes in lung function in patients with asthma is thus far unclear.
    • The most typical side effect of anticholinergics is dry mouth; other side effects include blurred vision, constipation, nausea, dizziness, and headache.

Definition of anticholinergic in US English:

anticholinergic

adjectiveˌantī-
  • (chiefly of a drug) inhibiting the physiological action of acetylcholine, especially as a neurotransmitter.

    (多指药物)抗胆碱能的

    Example sentencesExamples
    • He thought for a minute and added, ‘So, if we improve cognition by increasing acetylcholine, it makes sense that anticholinergic drugs can make dementia a lot worse.’
    • Amantadine, anticholinergic drugs, selegiline, and non-pharmacological treatments (such as physical therapy) provide symptomatic relief in mildly affected patients.
    • Antihistamine and anticholinergic drugs are relatively inexpensive.
    • They dismiss conventional medical treatment with anticholinergic drugs as inconvenient, unpleasant, and temporary, and they say that patients usually stop using anticholinergic drugs because of a dry mouth.
    • If these measures are not successful, an anticholinergic drug may control the pain.
    • Pharmacologic treatment of overactive bladder symptoms is based on the use of anticholinergic drugs that block the parasympathetic pathways and reduce detrusor muscle contraction.
    • Main outcome measures: Numbers of elderly people with new prescriptions of highly anticholinergic antidepressants and less anticholinergic antidepressants.
    • Thyrotoxicosis, anticholinergic drug poisoning, and amphetamine or cocaine use can result in signs of increased sympathetic activity and altered mental status.
    • Examples of anticholinergic drugs include atropine and ipratropium (Atrovent).
    • This agent crosses the blood-brain barrier and thereby reverses both central and peripheral effects of the abused anticholinergic drug.
    • This study demonstrates that moderate to severe dry mouth is common in patients treated with anticholinergic drugs.
    • Dry mouth is the most common complaint with the oral anticholinergic drugs oxybutynin and tolterodine.
    • The administration of antihypertensive and anticholinergic medications also impairs salivary functions and promotes xerostomia.
    • In each of these cases, once the iatrogenic etiology of this syndrome was recognized, the patients' symptoms improved rapidly and dramatically with administration of anticholinergic medication.
    • Use of the anticholinergic drug atropine during tap-water iontophoresis sometimes is helpful, but extreme caution is necessary to avoid toxicity from atropine overdose.
    • Older men with prostatic hypertrophy may benefit from alpha-blocker medications and should be watched for urinary retention if anticholinergic drugs are employed.
    • Although statistically significant, the differences between anticholinergic drugs and placebo were small, apart from the increased rate of dry mouth in patients receiving active treatment.
    • Medical management consists of maintenance therapy with anticholinergic inhibitors such as pyridostigmine to relieve symptoms and steroids to treat the autoimmunity.
    • Nonetheless, the available anticholinergic drugs (atropine and ipratropium bromide) have limited effects, perhaps because of their nonselectivity.
    • Until further research in primary care settings is performed, there is little evidence to guide family physicians in the choice of anticholinergic medications for urge incontinence.
nounˌantī-
  • An anticholinergic drug.

    抗胆碱能药

    Example sentencesExamples
    • Dry mouth, which can be brought on by neuroleptics, antidepressants, and anticholinergics, may worsen the problem.
    • However, the effect of chronic treatment with anticholinergics on airway remodeling, responsiveness, and changes in lung function in patients with asthma is thus far unclear.
    • Thus, in 1914, anticholinergics by injection or inhalation were considered as first-line asthma therapies.
    • Despite these uncertainties, anticholinergics are increasingly being used in both primary care and secondary care for the treatment of overactive bladder, and this has considerable implications for resources.
    • Concomitant use of anticholinergics and beta 2 agonists may be beneficial to the older patient
    • They recommend anticholinergics and antihistamines for the treatment of nausea associated with vertigo or motion sickness.
    • Medications that may worsen confusion include anticholinergics, analgesics, cimetidine, central nervous system depressants, lidocaine, and other medications.
    • Returning to our clinical scenario, we would recommend that our five-year-old patient with a moderate asthma exacerbation receive anticholinergics in addition to the [beta.sub.2] agonists and oral steroid therapy.
    • Probably the most common medications used for the treatment of incontinence fall into the general category of anticholinergics or drugs designed to ‘relax’ the bladder.
    • Moreover, anticholinergics do not appear to be effective for patients whose initial response to beta-agonists is impaired, and at this point, there is no clear consensus regarding their use.
    • Both antihistamines and anticholinergics can have anticholinergic side effects, including dry mouth, urinary retention, blurred vision, and exacerbation of narrow-angle glaucoma.
    • Agreement among guidelines is much greater regarding treatment - currently supporting the use of inhaled anticholinergics and antibiotics for initial treatment.
    • The most typical side effect of anticholinergics is dry mouth; other side effects include blurred vision, constipation, nausea, dizziness, and headache.
    • New medications, particularly anticholinergics and psychotropic medicines, should be the first suspects if there is a change in a patient's mental status.
    • Acute care of an asthma exacerbation involves the use of inhaled [beta.sub.2] agonists delivered by a metered-dose inhaler with a spacer, or a nebulizer, supplemented by anticholinergics in more severe exacerbations.
    • Anticholinergics have been used in an attempt to decrease gastric secretions and increase pH. As with the use of nasogastric tubes, anticholinergics do not decrease hospital stay or pain.
    • The medications most often used to help children with neurogenic bladder are called anticholinergics.
    • Because even small amounts can be fatal, anticholinergics constitute the most dangerous class of abused drugs.
    • These drugs are called anticholinergics and include oxybutynin, tolterodine, trospium chloride, and propiverine.
    • Short-term use of anticholinergics or antidiarrheal agents may be effective in combating incontinence associated with diarrhea.
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